Journal of Cutaneous Pathology 1983-Apr
Alternariasis: ultrastructure of skin granuloma.
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An ultrastructural investigation of dermal altenariasis has complemented previous studies. Alternaria tenuis was seen to be profusely present within the cytoplasm of multinucleate giant cells. Healthy elements were characterized by a thick, electron-lucent wall, ovoid osmiophilic inclusions and a poorly defined nucleus. Homogenous liquefaction and granular degeneration represented various types and steps of degradation; the wall subsisted for a while before collapsing and breaking into pieces. Penetration of the giant cell's cytoplasm within hollow tubes was observed.