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American Journal of Ophthalmology 2004-Jun

Bull's-eye maculopathy secondary to herbal toxicity from uva ursi.

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Lillian Wang
Lucian V Del Priore

关键词

抽象

OBJECTIVE

To report a case of bilateral bull's-eye maculopathy in a patient who ingested uva ursi, a known inhibitor of melanin synthesis, for 3 years before the onset of symptoms.

METHODS

Observational case report.

METHODS

Both eyes of a female patient were examined in the clinical practice setting.

RESULTS

A 56-year-old woman who ingested uva ursi for 3 years noted a decrease in visual acuity within the past year. Ocular examination including fluorescein angiography revealed a typical bull's-eye maculopathy bilaterally.

CONCLUSIONS

Uva ursi is a known inhibitor of melanin synthesis. It is necessary to broaden the list of potential retinal toxic drugs to include herbal adjuvants such as Uva Ursi and to elicit a history of their use in patients with unexplained ocular findings.

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