Chemical Study of Alkaloids from Corydalis conspersa.

From the whole plant of CORYDALIS CONSPERSA, four benzo[ C]-phenanthridine-type alkaloids were isolated. Three of these were identified as corynoline, acetylcorynoline and corynoloxine. The fourth is a new alkaloid, named consperine. Its structure, C (26)H (27)NO (7), has been established to be 6-acetonylacetylcorynoline on the basis of spectral data and chemical synthesis. The configuration of acetonyl group in consperine is also discussed.