[Fluoride tolerance in cases of dental caries and fluorosis].

32 volunteers (18-20-year-olds) without concomitant diseases were divided into 3 groups: with high caries incidence (1), with dental fluorosis of different degrees (2) and with completely intact dentition (3). Dynamics of ionized F in blood serum and mixed saliva after single sodium fluoride burden (F-dosage=0.1 mg/kg body weight) was determined 1, 2, 3, 5, 7 and 24 hours after per os consumption by Orion-9609-BN F-selective electrode. F bound by organic material was assayed after breaking covalent bond C-F by sodium diphenyl. It was common for all participants that wide range of sensitivity to ingested F but F-tolerance had reversed trends in caries and fluorosis. Content of organic "fluoride" in blood serum changed insignificantly. In mixed saliva the dynamics of ionized F in dental caries and fluorosis conditions followed to some extent blood serum trends.