Zeitschrift für Naturforschung - Section C Journal of Biosciences
Hepatoprotective triterpenes from hairy root cultures of Ocimum basilicum L.
只有注册用户可以翻译文章
登陆注册
链接已保存到剪贴板
关键词
抽象
Six triterpene acids identified as betulinic, oleanolic, ursolic, 3-epimaslinic, alphitolic and euscaphic acids have been isolated from a dichloromethane extract of hairy root cultures of Ocimum basilicum L. (Lamiaceae). These cultures were obtained by genetic transformation using Agrobacterium rhizogenes. The extract as well as the isolated compounds were evaluated for their hepatoprotective activity by measuring their effect on the oxidative stress status of liver, induced by carbon tetrachloride, in albino rats and in liver homogenate in vitro. All tested compounds displayed hepatoprotective activity comparable to oleanolic and ursolic acids.