Cancer Letters 2004-Aug
Inhibition of metalloproteinase activity by fruit extracts.
只有注册用户可以翻译文章
登陆注册
链接已保存到剪贴板
关键词
抽象
While the metalloproteinase enzymes are essential for development and remodeling of tissues, aberrant over expression of these enzymes contributes to several pathologic conditions. In particular, metalloproteinase over expression in cancer plays a significant role in metastasis by providing a mechanism for invasion and spread. The data presented here indicate that water extracts of raspberries, blackberries and muscadine grapes inhibit the activities of metalloproteinases 2 and 9. This inhibition could contribute to the suppression of carcinogenesis by diets high in fruit content.