Journal of Natural Products 2011-Jan
Sesquiterpenes from Chloranthus japonicus.
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Eight new sesquiterpene lactones (chlorajapolides A-E, 1-5, chlorajaposide, 6, chlorajaponol, 7, and chloraeudolide, 8) were isolated from an ethyl acetate-soluble partition of the ethanol extract of the whole plants of Chloranthus japonicus. The structures and relative configurations of 1-8 were established on the basis of spectroscopic data analysis. All isolates obtained were evaluated for their cytotoxic activity against a small panel of cancer cell lines.