Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 2016-Feb
[Study on Alkaloids of Fruit from Macleaya cordata].
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To study the alkaloids from the fruit of Macleaya cordata.
The alkaloids were isolated and purified by silica gel column chromatography and preparative high performance liquid chromatography,and the structures were elucidated based on the spectral data.
Eight alkaloids were obtained from the fraction of ethanol extract and identified as 6-cyanodihydrosanguinarine( 1),6-acetonyldihydrosanguinarine( 2),6-acetonyldihydrochelerythrine( 3),chelerythrine( 4),dihydrochelerythrine( 5),13,14-dehydrogen-N-methyl-coptisine( 6),N-methyl-canadine( 7) and berberine( 8).
Compounds 1 and 6 are new nature products,and compound 7 is isolated from this plant for the first time.