amyloid/atrophy

The present invention was made utilizing funds from the National Institute of Ageing, grant numbers AG-05443, AG-05133 and AG-08974. This application is a continuation-in-part of U.S. patent application Ser. No. 08/640,704, now abandoned, and also a continuation-in-part of International Patent

TECHNICAL FIELD & BACKGROUND Imaging of amyloid-beta plaques (including amyloid, amyloid-beta peptides) and other pathology and anatomical features in the retina or brain is often unobtainable without the use of specialized contrast agents, or autofluorescence techniques. While drusen and

TECHNICAL FIELD & BACKGROUND Imaging of amyloid-beta plaques including amyloid, amyloid-beta peptides and other pathology and anatomical features in a patient user's retina or a patient user's brain is often unobtainable without the utilization of specialized contrast agents or autofluorescence

BACKGROUND OF THE INVENTION The present invention relates to the identification of compounds that are suitable for imaging amyloid deposits in living patients. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of

BACKGROUND OF THE INVENTION The present invention relates to the identification of compounds that are suitable for imaging amyloid deposits in living patients. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of

FIELD OF THE INVENTION The present invention relates to antigen binding proteins, including antibodies, that bind .beta.-amyloid peptide and in particular human .beta.-amyloid peptide. The present invention also concerns methods of treating diseases or disorders characterised by elevated

BACKGROUND OF THE INVENTION 1. Field of the Invention The invention relates to the use of natural product compounds isolated from plants, and synthetic chemical analogues thereof, for the prevention and treatment of beta-Amyloid protein-induced disease. Specifically, the invention relates to

This application is a 371 of International Application No. PCT/EP2008/062652, filed Sep. 23, 2008, which claims the priority of GB Application No. 0718737.0, filed Sep. 25, 2007, which are incorporated herein in their entirety. FIELD OF THE INVENTION The present invention relates to methods of

TECHNICAL FIELD This invention generally relates to protein chemistry, cell biology, neuroscience and medicine. The invention provides compositions comprising protein aggregation inhibitors, and pharmaceutical compositions comprising them, and methods for making and using them, including methods for

TECHNICAL FIELD This invention generally relates to protein chemistry, cell biology, neuroscience and medicine. The invention provides compositions for increasing the clearance of protein aggregates such as amyloid beta protein (A.beta.) aggregates, and pharmaceutical compositions comprising them,

FIELD OF THE INVENTION The present invention relates to novel compounds and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as medicaments for treatment and/or prevention of various diseases. In particular the invention relates to

The present invention relates to compounds and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as medicaments for treatment and/or prevention of various diseases. In particular the invention relates to compounds, which are

The present invention relates to compounds and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as medicaments for treatment and/or prevention of various diseases. In particular the invention relates to compounds, which are

TECHNICAL FIELD OF THE INVENTION The present invention relates to novel compounds and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of A.beta.-related pathologies such as Downs syndrome, .beta.-amyloid

The present invention relates to compounds and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as medicaments for treatment and/or prevention of various diseases. In particular the invention relates to compounds, which are