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FIELD OF THE INVENTION
The present invention relates to an analgesic formulation for pain control not limited to postoperative pain control.
BACKGROUND OF THE INVENTION
The treatment and relief of pain is one of the most common reasons patients seek medical evaluation. Pain has been defined by the
BACKGROUND TO THE ART
The current means of combating migraine attacks include simple analgesics such as aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDS) and paracetamol, taken at the earliest signs of an attack [1,2,3]. Aspirin, paracetamol and phenacetin have long been among the most
BACKGROUND OF THE INVENTION
The administration of therapeutic doses of morphine and other clinically useful narcotic analgesics is often accompanied by unpleasant side effects on the gastro-intestinal system. For instance, morphine and related opiates such as meperidine and methadone may retard
BACKGROUND
The administration of therapeutic doses of morphine and other clinically useful narcotic analgesics is often accompanied by unpleasant side effects on the gastro-intestinal system. For instance, morphine and related opiates such as meperidine and methadone may retard intestinal mobility
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is relevant to the field of suppressing sensory afferent neuron mediated symptoms and the manufacture of agents and compositions which suppress the same.
2. Discussion of the Related Art.
Sensory afferent nerves mediate a
BACKGROUND OF THE INVENTION
Morphine or other bimodally-acting opioid agonists are administered to relieve severe pain due to the fact that they have analgesic effects mediated by their activation of inhibitory opioid receptors on nociceptive neurons (see North, Trends Neurosci., Vol. 9, pp. 114-117
FIELD OF THE INVENTION
This invention relates to magnesium-based compositions for treating migraine headaches, and methods for using the same.
BACKGROUND OF THE INVENTION
Analgesic compositions comprising magnesium salts have been used to treat a variety of ailments as well as reduce the gastric
FIELD OF THE INVENTION
This invention relates to magnesium-based analgesic compositions for treating migraine headaches, and methods for using the same.
BACKGROUND OF THE INVENTION
Analgesic compositions comprising magnesium salts have been used to treat a variety of ailments as well as reduce the
BACKGROUND
.DELTA..sup.9 -Tetrahydrocannabinol, the pyschoactive marijuana derived cannabinoid, binds to the CB1 receptor in the brain and to the CB2 receptor in the spleen. Compounds which stimulate the CB1 receptor have been shown to induce analgesia and sedation, to cause mood elevation, to
BACKGROUND
.DELTA..sup.9 -Tetrahydrocannabinol, the pyschoactive marijuana derived cannabinoid, binds to the CB1 receptor in the brain and to the CB2 receptor in the spleen. Compounds which stimulate the CB1 receptor have been shown to induce analgesia and sedation, to cause mood elevation, to
BACKGROUND
.DELTA..sup.9 -Tetrahydrocannabinol, the psychoactive marijuana derived cannabinoid, binds to the CB1 receptor in the brain and to the CB2 receptor in the spleen. Compounds which stimulate the CB1 receptor have been shown to induce analgesia and sedation, to cause mood elevation, to
BACKGROUND
.DELTA..sup.9 -Tetrahydrocannabinol, the pyschoactive marijuana derived cannabinoid, binds to the CB1 receptor in the brain and to the CB2 receptor in the spleen. Compounds which stimulate the CB1 receptor have been shown to induce analgesia and sedation, to cause mood elevation, to
FIELD OF THE INVENTION
This invention relates to water-soluble polymer conjugates of biologically active molecules, and in particular, to water-soluble polymer conjugates of opioid antagonists, such as naloxone, and related pharmaceutical compositions and uses thereof.
BACKGROUND OF THE
FIELD OF THE INVENTION
This invention relates to water-soluble polymer conjugates of biologically active molecules, and in particular, to water-soluble polymer conjugates of opioid antagonists, such as naloxone, and related pharmaceutical compositions and uses thereof.
BACKGROUND OF THE
FIELD OF THE INVENTION
This invention relates to water-soluble polymer conjugates of biologically active molecules, and in particular, to water-soluble polymer conjugates of opioid antagonists, such as naloxone, and related pharmaceutical compositions and uses thereof.
BACKGROUND OF THE