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RELATED APPLICATION
This application claims the benefit of Indian Application No. 201611037409, filed Nov. 2, 2016. The entire content of that application is hereby incorporated by reference.
FIELD OF THE INVENTION
The present invention relates to C5, C6 substituted and/or fused oxindole compounds
BACKGROUND
Cancer is one of the leading causes of death in Americans. Drugs that can prevent or limit metastasis, growth, or invasive properties of cancer in mammals have the potential for life saving use in humans. Metastasis is one of the predominant factors in the mortality of cancer patients.
CROSS-REFERENCE TO RELATED APPLICATION
This application claims priority to and is a 35 U.S.C. .sctn. 371 national phase application of PCT/KR2015/001889 (WO2015/130109), filed on Feb. 26, 2015 entitled "Pharmaceutical Composition for Cancer Treatment Containing Gossypol and Phenformin as Active
FIELD OF INVENTION
The present invention relates to dihydroartemisinin and dihydroartemisitene dimers and their use in the treatment of cancer and as antiprotzoal agents.
BACKGROUND OF THE INVENTION
Cancer deaths in the U.S. alone were over 500,000 in 2001, and in spite of many advances, cancer
FIELD OF THE INVENTION
The present invention relates to dihydroartemisinin and dihydroartemisitene dimers and their use in the treatment of cancer and as antiprotzoal agents.
BACKGROUND OF THE INVENTION
Cancer deaths in the U.S. alone were over 500,000 in 2001, and in spite of many advances, cancer
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to anti-neoplastic compositions and methods for application thereof and, more particularly, to such compositions and methods which have been discovered to be of particular value in the treatment of tumors,
The present invention relates to platinum(II) complexes useful as anti-tumour agents, to a method for their preparation and to pharmaceutical compositions containing them.
BACKGROUND OF THE INVENTION
It is well known the wide interest on platinum(II) and Platinum(IV) complexes as anti-tumour
FIELD OF INVENTION
This invention relates to the inhibition, reduction and prevention of cancer. More particularly, the invention relates to compounds and methods for inhibiting skin cancer, prostate cancer and pancreatic cancer.
BACKGROUND OF THE INVENTION
Chemoprevention has become an effective
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to new tropolone derivatives useful as anti-tumor agents and represented by the general formula (I): ##STR3## wherein R.sup.1 represents H or an alkyl group, R.sup.2 represents an alkyl, aryl, aralkyl or heterocyclic
TECHNICAL FIELD
This invention relates to compounds that inhibit growth of breast cancer cells.
BACKGROUND
Breast cancer is one of worst diseases suffered by human beings. Due to the continuing development of drug resistance, there is always a need for the new drugs or lead
BACKGROUND OF INVENTION
The signal transducers and activators of transcription (STATs) are key signal transduction proteins that play a dual role of transducing biological information from cell surface receptors to the cytoplasm and translocating to the nucleus where, as transcription factors, they
BACKGROUND OF INVENTION
The signal transducers and activators of transcription (STATs) are key signal transduction proteins that play a dual role of transducing biological information from cell surface receptors to the cytoplasm and translocating to the nucleus where, as transcription factors, they
RELATED APPLICATIONS
The present application is a National Stage of PCT/CN2011/072530 filed Apr. 8, 2011, and claims priority from, Chinese Application No. 201010165908.X filed May 10, 2010.
FIELD OF THE INVENTION
The present invention relates to an anti-tumor plant-medicament sustained-release
RELATED APPLICATIONS
This application is a national stage application filed under 35 USC 371 of PCT/JP2015/052431, filed Jan. 29, 2015, which claims the benefit of Japanese Patent Application No. 2014-014389, filed Jan. 29, 2014, and Japanese Patent Application No. 2014-229652, filed Nov. 12, 2014
TECHNICAL FIELD
The present invention is directed to a therapeutic method for treating human tumors. More specifically, the present invention is directed to a method of treating human tumors with monoclonal antibodiies in combination with lentinan.
BACKGROUND OF THE INVENTION
In previous studies it