antidiabetic/inflammation

This invention relates to novel structural analogs of corosolic acid having anti-diabetic and anti-inflammatory properties. These compounds are found to exhibit potent hypoglycemic, 5-lipoxygenase inhibitory and antitumor activities. TECHNICAL FIELD Diabetes is perceived as a disorder of metabolism,

BACKGROUND OF THE INVENTION There are a number of organic compounds listed in the chemical literature which contain a 2-iminoimidazolidine nucleus: ##STR2## Among the known compounds are 1-[p-(2-aminoethyl)phenylsulfonyl]-3-butyl-4-ethyl-2-iminoimidazolidine and

The present invention is directed to processes of isolating purified compositions with or without chromium containing compounds, from a variety of natural sources including, but not limited to, a yeast strain S. carlsbergensis, or S. cerevisiae, or any commercial source of yeast extract; or from the

TECHNICAL FIELD OF THE INVENTION The present invention provides a new, non-toxic Vitex leucoxylon extract for inhibiting increase of blood sugar level or lowering blood glucose levels and a process for extracting the same from the plant material. Isolated corosolic acid from the extract is also

FIELD OF THE INVENTION The present invention relates to therapeutic methods and pharmaceutical compositions employing native hepoxilins and hepoxilin analogs. BACKGROUND OF THE INVENTION Hepoxilins are biologically active hydroxy epoxide derivatives of arachidonic acid formed through the

The present invention is directed to processes of isolating purified compositions with or without chromium containing compounds, from a variety of natural sources including, but not limited to, a yeast strain S. carlsbergensis, or S. cerevisiae, or any commercial source of yeast extract; or from the

2. FIELD OF THE INVENTION The present invention relates to salt forms of a potent modulator of the peroxisome proliferator-activated receptor .gamma. ("PPAR .gamma.") receptor and polymorphic forms thereof, compositions comprising the salt forms or polymorphic forms, methods of making the salt forms

2. FIELD OF THE INVENTION The present invention relates to salt forms of a potent modulator of the peroxisome proliferator-activated receptor .gamma.("PPAR.gamma.") receptor and polymorphic forms thereof, compositions comprising the salt forms or polymorphic forms, methods of making the salt forms

BACKGROUND OF THE INVENTION There are a number of organic compounds listed in the chemical literature which contain a 2-iminoimidazolidine nucleus: ##STR2## Among the known compounds are 1-[p-(2-aminoethyl)-phenylsulfonyl]-3-butyl-4-ethyl-2-iminoimidazolidine and

BACKGROUND OF THE INVENTION There are a number of organic compounds listed in the chemical literature which contain a 2-iminoimidazolidine nucleus: ##STR2## Among the known compounds are 1-[p-(2-aminoethyl)phenylsulfonyl]-3-butyl-4-ethyl-2-iminoimidazolidine and

BACKGROUND OF THE INVENTION There are a number of organic compounds listed in the chemical literature which contain a 2-iminoimidazolidine nucleus: ##STR2## Among the known compounds are 1-[p-(2-aminoethyl)-phenylsulfonyl]-3-butyl-4-ethyl-2-iminoimidazolidine and

BACKGROUND OF THE INVENTION There are a number of organic compounds listed in the chemical literature which contain a 2-iminoimidazolidine nucleus: ##STR2## Among the known compounds are 1-[p-(2-aminoethyl)phenylsulfonyl]-3-butyl-4-ethyl-2-iminoimidazolidine and

1. FIELD OF THE INVENTION The invention relates to cycloalkyl-hydroxyl compounds and pharmaceutically acceptable salts, hydrates, solvates, and mixtures thereof; compositions comprising a hydroxyl compound or a pharmaceutically acceptable salt, hydrate, solvate, or mixtures thereof; and methods for

1. FIELD OF THE INVENTION The invention relates to cycloalkyl-hydroxyl compounds and pharmaceutically acceptable salts, hydrates, solvates, and mixtures thereof; compositions comprising a hydroxyl compound or a pharmaceutically acceptable salt, hydrate, solvate, or mixtures thereof; and methods for

1. FIELD OF THE INVENTION The invention relates to cycloalkyl-hydroxyl compounds and pharmaceutically acceptable salts, hydrates, solvates, and mixtures thereof; compositions comprising a hydroxyl compound or a pharmaceutically acceptable salt, hydrate, solvate, or mixtures thereof; and methods for