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aristolochia esperanzae/necrosis
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11 结果
BACKGROUND
The active compounds or metabolites of herbal plants exert a definite physiological action on the human body and thus are widely used in human therapy for various diseases including cancer. Previous studies by our group have reported the anticarcinogenic properties of the two herbal
Fatal renal failure due to the Chinese herb "GuanMu Tong" (Aristolochia manshuriensis): autopsy findings and review of literature.
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Herbal remedies have been used since ancient times and it is now known that they are not completely free of adverse effects. We present the case of a 41-year-old Chinese man, who died in renal failure because he consumed a herbal preparation called "Fen Qing Wu Lin Wan", having GuanMu Tong as main
Ethnopharmacological Relevance
Aristolochia paucinervis (A. paucinervis) (Aristolochiaceae) is a plant frequently used in Moroccan alternative medicine. The aim of the current study is to investigate the phytochemical composition of rhizomes decoction of A.Long-term outcome of acute renal injury induced by Aristolochia manshuriensis Kom in rats.
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OBJECTIVE
To investigate the long-term functional and morphological changes of the kidney induced by acute intoxication of Aristolochia manshuriensis Kom in rats.
METHODS
Experimental model of acute renal injury was established in the Sprague-Dawley rats with oral administration of decoctions of
The sequential development of the clinical signs and lesions in the organs of Nubian goats fed on Aristolochia bracteata (Um Galagel) and Cadaba rotundifolia (Kurmut) and their mixture in certain proportions was studied. Kidney and liver function was tested and the results correlated with
Aristolochia trilobata: Identification of the Anti-Inflammatory and Antinociceptive Effects.
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Aristolochia trilobata, popularly known as "mil-homens," is widely used for treatment of stomach aches, colic, asthma, pulmonary diseases, diabetes, and skin affection. We evaluated the antinociceptive and anti-inflammatory activities of the essential oil (EO) and the main
Aristolochic acid and its derivatives as inhibitors of snake venom L-amino acid oxidase.
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Snake venom L-amino acid oxidase (LAAO) exerts toxicity by inducing hemorrhage, pneumorrhagia, pulmonary edema, cardiac edema, liver cell necrosis etc. Being well conserved, inhibitors of the enzyme may be synthesized using the template of the substrate, substrate binding site and features of the
The nephrotoxicity of Aristolochia manshuriensis in rats is attributable to its aristolochic acids.
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BACKGROUND
Although Aristolochia manshuriensis (AM), which was incriminated in the Japanese variety of Chinese herbs nephropathy, has been recently shown to be nephrotoxic in rats, less is known about whether this toxicity is attributable to its aristolochic acids (AA). We compared the renal effect
A new sesquiterpene, a new monoterpene and other constituents with anti-inflammatory activities from the roots of Aristolochia debilis.
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A new sesquiterpene (1) and a new monoterpene (2), together with thirteen known compounds (3-15) were isolated from an ethanol extract of the roots of Aristolochia debilis Sieb. et Zucc. The structures of compounds 1 and 2 were elucidated using HR-ESI-MS, 1D and 2D NMR spectroscopy.
Aristolochic acids induce chronic renal failure with interstitial fibrosis in salt-depleted rats.
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Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia fangchi) containing nephrotoxic and carcinogenic aristolochic acids (AA). This study attempted to reproduce the main features of human CHN (renal failure, tubular
Kidney toxicity related to herbs and dietary supplements: Online table of case reports. Part 3 of 5 series.
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BACKGROUND
No tabular summary of potentially life-threatening, kidney-toxic dietary supplements (DS; includes herbs) based on PubMed case reports is currently available online and continually updated to forewarn United States consumers, clinicians, and companies manufacturing DS. The purpose of this
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*所有信息均基于已发表的科学研究
