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The utility of blood-brain barrier (BBB) biomarkers for clinical and magnetic resonance imaging progression in multiple sclerosis (MS) has not been extensively investigated.
To determine whether cerebrospinal fluid (CSF) measures of BBB at clinical onset predict radiological and clinical
We performed an observational study to investigate if plasma 5-hydroxyindole-3-acetic acid (5-HIAA), a derivative end product of serotonin (5-hydroxytryptamine), concentration could be a predictor for deterioration of urinary albumin excretion. The relationship between baseline plasma 5-HIAA
The transport of intrathecally administered iodine131-albumin to the circulating plasma was measured in five patients with cerebral atrophy and three with communicating hydrocephalus. The percentage of the administered dose in plasma 24 hours after injection in both groups was lower than reported by
Malnutrition among dementia patients is an important issue. However, the biochemical markers of malnutrition have not been well studied in this population. The purpose of this study was to compare biochemical blood markers among patients with Alzheimer's disease (AD), dementia with Lewy bodies
The present study was conducted to develop a special formula to predict creatinine clearance (CCr, ml/min) in the elderly with chronic muscle atrophy using serum albumin (Alb, g/dl). We obtained 90 data sets including actual body weight (BW, kg), urinary creatinine excretion (UCr, mg/24 h), serum
AIMS/INTRODUCTION
To investigate the association of alternative glycemic measures-namely, serum glycated
albumin (GA), hemoglobin A
1c (HbA
1c ), and the GA/HbA
1c ratio-with global brain and hippocampal
atrophy in a general elderly Japanese
Glycated albumin (GA) reflects shorter term glycemic control state than HbA1c. This study evaluated whether GA is useful for early detection of deterioration of glycemic control state after discharge from educational admission. Among the patients with educational admission, this study included 21
Accessibility of tyrosiles in serum albumin of healthy rabbits and those with experimental fatty degeneration of the liver was studied by the termal parturbation spectroscopy. The method determined about 50% of perturbed tyrosiles in albumin of healthy rabbits. Serum albumin of rabbits with fatty
BACKGROUND
Our recent study clarified that gut ischemia-reperfusion (I/R) causes gut-associated lymphoid tissue (GALT) mass atrophy, a possible mechanism for increased morbidity of infectious complications after severe surgical insults. Because albumin administration reportedly reduces hemorrhagic
Valvular heart diseases are associated with significant cardiovascular morbidity and mortality, and often require surgical and/or percutaneous repair or replacement. Valve replacement is limited to mechanical and biological prostheses, the latter of which circumvent the need for lifelong
We delineate a complication of hypoalbuminemia in dentatorubral-pallidoluysian atrophy (DRPLA), which we have found to be common in this disorder. In addition, we explored the pathogenesis of this phenomenon through clinical and histological examinations. Clinical course and laboratory findings of
Retinal degeneration diseases affect millions of patients worldwide and lead to incurable vision loss. These diseases are caused by pathologies in the retina and underlying choroid, located in the back of the eye. One of the major challenges in the development of treatments for these BACKGROUND
Currently, no unequivocal predictors of disease evolution exist in patients with multiple sclerosis (MS). Cortical atrophy measurements are, however, closely associated with cumulative disability.
OBJECTIVE
Here, we aim to forecast longitudinal magnetic resonance imaging (MRI)-driven
We recently found that serum dehydroepiandrosterone sulfate (DHEA-S) concentration correlated inversely with the degree of urinary albumin excretion in a cross-sectional study. We therefore performed an observational study to investigate the relationship between serum DHEA-S concentrations and
From this investigation, it is apparent that owing to the superior diagnostic differentiating of udder conditions by means of the IDF/BSA criteria, a range of detailed data has become available which facilitates an unprecedented insight in the dynamic balancing during normal lactation of several