berberis laurina/hypersensitivity

The protoberberine alkaloid berberine is isolated as a main alkaloid from the roots and bark of Berberis vulgaris. Berberine strongly inhibited in vitro the proliferative response of mouse spleen cells to T-dependent mitogens concanavalin A (Con A) and phytochemagglutinin (PHA). Spleen cells

Psoriasis vulgaris is a skin disease with a multi-factorial genesis where no causal treatment is known. Based on our own pilot studies, we set up a randomized, placebo-controlled clinical trial to evaluate the efficacy and safety of Mahonia aquifolium bark extract in psoriasis patients. From autumn

Extracts obtained from the roots of Berberidaceae species have been used in Eastern and Bulgarian folk medicine in rheumatic and other chronic inflammatory disorders. The investigations of the chemical composition and immunological properties show that their activity is mainly due to the alkaloid