Three saponins, craniosaponin A (1) and buddlejasaponins Ia (2) and I (3) were isolated from the n-butanol soluble fraction of Craniotome furcata for the first time. Among them, craniosaponin A (1) was identified to be a new compound. The structure of craniosaponin A was assigned mainly by spectral
Craniotome furcata (Link) O. Kuntze (Lamiaceae) has been reported worldwide as the only species of the genus Craniotome. Traditionally, this plant is used in the treatment of wounds. Craniosides A and B, buddlejasaponins I, and essential oils have been isolated from the genus Craniotome.