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OBJECTIVE
To know the effect of neoadjuvant chemotherapy on surgical outcomes (R1 resections, post-operative complications, recurrence and follow up) in Stage IV borderline operable cancers of oral cavity.
METHODS
Patients in group A (n=45) were those who were referred for neoadjuvant chemotherapy
OBJECTIVE
To determine the incidence of dental caries in 64 leukemic children who received dental treatment before the initiation of chemotherapy and had intensive oral care during the course.
METHODS
Caries experience (deft/DMFT), white-spot lesions (enamel demineralization), premature primary
Effects of preoperative chemotherapy with three courses of a combination of bleomycin, vincristine, mitolactol, prednisolone and methotrexate, with a leucovorin rescue, followed by surgery, were studied in 43 patients with advanced squamous cell carcinoma of the oral region. Prior to chemotherapy 32
The results of the preoperative Co 60 irradiation and BVMM (bleomycin, vincristine, mitolactol, methotrexate) chemotherapy were compared. Both treatments were used in 50-50 advanced squamous cell cancer of the oral cavity. The general condition, size of lesion and age of the patients were similar.
A 53-year-old man presented with a continuous high fever and was diagnosed with diffuse large B-cell lymphoma with metastasis to the lung, spleen, and mesenterium. He was treated with cyclophosphamide and prednisolone followed by administration of cyclophosphamide, doxorubicin, vincristine, and
Between February 1978 and January 1984, 222 eligible patients were randomised in a multicentre trial of preoperative intra-arterial chemotherapy in the treatment of oral cavity and oropharynx carcinoma. Patients were randomised between either surgery or preoperative chemotherapy. This latter group
Thirty-one patients with refractory ovarian cancer and other malignancies principally confined to the abdominal cavity were treated with an intraperitoneal combination-chemotherapy regimen consisting of cisplatin (100 to 200 mg/m2), cytosine arabinoside (10(-4) to 10(-3) mol/L) and doxorubicin (2 to
OBJECTIVE
The present study aimed to investigate the efficacy, toxicity, and impact of induction chemotherapy (IC) in locally advanced T4b oral cavity squamous cell cancers (OSCCs).
METHODS
Patients diagnosed with locally advanced T4b OSCC from January 2013 to October 2016 at our center, who
UNASSIGNED
The present study aimed to investigate the efficacy, toxicity, and impact of induction chemotherapy (IC) in technically unresectable T4a oral cavity squamous cell cancers (OSCCs).
UNASSIGNED
Patients diagnosed with technically unresectable locally advanced T4a OSCC from January 2013 and
There is a lack of data from phase III randomized studies to support an ideal approach for locally advanced oral cavity cancer patients. In general, surgery, radiotherapy and chemotherapy are valid treatment options, and combined approach is usually indicated given poor clinical outcomes with single
BACKGROUND
Locoregionally advanced oral cavity cancers are aggressive tumours with high risk of relapse after definitive treatment. This study was performed to assess the effectiveness and safety of induction chemotherapy prior to surgery for untreated oral cavity cancer patients.
METHODS
Only
OBJECTIVE
The objective of the following study is to investigate the efficacy and impact of induction chemotherapy in T4b oral cavity cancers.
METHODS
It's a retrospective analysis of prospectively collected data of T4b oral cavity cancer patients who were offered induction chemotherapy and then
BACKGROUND
Locally advanced and unresectable oral cavity cancers have a poor prognosis. Induction might be beneficial in this setting by reducing tumor bulk and allowing definitive surgery.
OBJECTIVE
To analyze the impact of induction chemotherapy on locally advanced, technically unresectable oral
We studied the usefulness and safety of long-term administration of uracil and tegafur (UFT) after primary therapy of the malignant tumor in jaw and oral cavity regions randomized controlled trial. 112 cases were totallized 6 institutes belonging to the Oral Surgery Malignant Tumor Research
OBJECTIVE
To report outcomes of oral cavity cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy (chemoIMRT).
METHODS
Between 2001 and 2004, 21 patients with oral cavity squamous cell carcinoma underwent definitive chemoIMRT. Sites included were oral tongue (n =