Ceralyte® will be administered during the first 24-hours post-burn. Fluid requirements will be calculated according to the Parkland Formula with 50% administered during the first 8 hours and the second 50% administered over the next 16 hours. During the first 2 hours IV fluids will be started at the Parkland goal minus 250cc, which will be administered using Ceralyte via oral, nasogastric (NG), or dobhoff tube. ORT and IV fluids will be monitored with additional doses given hourly. Urine output will be monitored hourly and gastric residuals will be monitored every 2 hours, with adjustments made as needed to ensure adequate fluid resuscitation.

Ceralyte 90® was administered during first 24-hours post-burn. Fluid requirements were calculated according to Parkland Formula: 50% administered during first 8 hours, 50% administered over next 16 hours. During first 2 hours IV fluids were started at Parkland goal minus 250cc, which was administered using Ceralyte via oral, NG, or dobhoff tube. ORT and IV fluids were monitored with additional doses given hourly. Urine output was monitored hourly and gastric residuals were monitored every 2 hours, with adjustments made as needed to ensure adequate fluid resuscitation.

Oral Rehydration Therapy

Sex: Female, Male

Race (NIH/OMB)

Region of Enrollment

Number of participants whose IV fluids were reduced to less than or equal to 80% of the Parkland Goal IV resuscitation formula within the first 24 hours of initial burn injury.
To test the efficacy and safety of Oral RehydrationTherapy in resuscitation of burn patients

Number of Participants With a 20% Decrease in Required IV Fluid.

Ceralyte 90® was administered during first 24-hours post-burn. Fluid requirements were calculated according to Parkland Formula: 50% administered during first 8 hours, 50% administered over next 16 hours. During first 2 hours IV fluids were started at Parkland goal minus 250cc, which was administered using Ceralyte via oral, nasogastric, or dobhoff tube. ORT and IV fluids were monitored with additional doses given hourly. Urine output was monitored hourly and gastric residuals were monitored every 2 hours, with adjustments made as needed to ensure adequate fluid resuscitation.

Overall Study

Carisa Cooney

Burn Any Degree Involving 20-29 Percent of Body Surface

Burn Any Degree Involving 30-39 Percent of Body Surface

Burn Any Degree Involving 40-49 Percent of Body Surface

Burn Any Degree Involving 50-59 Percent of Body Surface

Burn Any Degree Involving 60-65 Percent of Body Surface

Fluid Resuscitation

This is a prospective pilot study of patients with moderate-major burn wounds (20-65% TBSA).
Patients who meet inclusion/exclusion criteria will be enrolled in the study upon admission to the Burn Unit.
Fluid requirements will be calculated according to the Parkland Formula (4 cc/kg/% Total Body Surface Area) administered over 24 hours since time of injury.
5. Patients will be monitored according to standard of care.
a. If gastric residuals are >300cc, ORT will be stopped and only IV fluid resuscitation will be used.

CeraLyte 90

Johns Hopkins Bayview Burn Center

Oral Rehydration Therapy in Burn Patients

Oral Rehydration Therapy in Burn Patients Phase 1

Only 3 patients were enrolled. No statistical analyses were performed.

Johns Hopkins University

Diarrhoea

Severe Malnutrition

Amylase resistant starch added ORS

ICDDR,B

Oral Rehydration SolutionContaining Amylase Resistant Starch in Severely Malnourished Children.

Oral Rehydration SolutionContaining Amylase Resistant Starch in Severely Malnourished Children With Watery Diarrhoea Due to Vibrio Cholerae

International Centre for Diarrhoeal Disease Research, Bangladesh

Nestlé Foundation

cholera

edema

cholera/edema

Oral Rehydration Therapy in Burn Patients

Oral Rehydration SolutionContaining Amylase Resistant Starch in Severely Malnourished Children.

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