cinchona/potassium

A method for the determination of Cinchona extract (whose main components are the alkaloids cinchonine, cinchonidine, quinidine, and quinine) in beverages by liquid chromatography was developed. A beverage with an alcohol content of more than 10% was loaded onto an OASIS HLB solid-phase extraction

The enantioselective synthesis of a potent Maxi-K potassium channel opener (BMS-204352) mediated by N-fluoroammonium salts of cinchona alkaloids is described. Two synthetic pathways were evaluated. An ee as high as 88% was achieved (>99% after a single recrystallisation).

Singly-charged complexes of (8S,9R)-tert-butylcarbamoylquinine (tBuCQN), N-3,5-dinitrobenzoyl-(S,R)-leucine (DNB-S/R-leucine), and alkali metal counter ions (Li(+), Na(+), K(+)) were investigated by density-functional theory. It is shown that the cations prefer formation of an ionic pair with the

The effects of quinine, quinidine, cinchonine, cinchonidine and chloroquine on phospolipid synthesis in the Jurkat T cell line have been compared. It was found that the two potassium channel blockers, quinine and quinidine, markedly enhanced phosphatidylserine synthesis and strongly decreased both