citrate/neoplasms

The uptake of gallium citrate Ga67 and ferrous citrate Fe59 was studied in pregnant rats with or without a 4-dimethylamino-stilben(DS)-induced sarcoma tumor. The liver and placenta of the mother concentrated 67Ga, while the uptake of 67Ga in the embryo was minimal. However, the embryo showed higher

The authors analyzed the results of thermographic and scintigraphic (using 67Ga-citrate produced in the USSR) investigations in 41 patients: 10 with tumors of the oral cavity, 12 with oropharyngeal tumors, and 19 with parapharyngeal tumors. Of the latter 10 had morphologically verified benign

Using in vivo and in vitro experimental models, the uptake and excretion of 67Ga-citrate in tumor cells and normal cells were studied. The time-lapse accumulation of 67Ga in the tumor of rats bearing Yoshida sarcoma reached its peak 24 h after the administration of 67Ga and gradually decreased

Using in vivo and in vitro experimental models, the uptake and excretion of 67Ga-citrate in tumor cells and normal cells were studied. The time-lapse accumulation of 67Ga in the tumor of rats bearing Yoshida sarcoma reached its peak 24 h after the administration of 67Ga and gradually decreased

169-Yb-citrate was used as the tumor-scanning agent in 360 patients with malignant tumors and in 55 others with benign lesions and the results compared with 67-Ga-citrate studies in other series. In malignant tumors, the overall positive detection rate for ytterbium was 65.3%; in benign lesions, the

The management of advanced or recurrent prostate cancer is limited in part by the lack of effective imaging agents. Metabolic changes in prostate cancer have previously been exploited for imaging, culminating in the recent US FDA approval of [11C]choline for the detection of subclinical recurrent

Two tumour-imaging agents, 67Gallium-citrate and 111Indium-bleomycin have been assessed in a clinical trial. Both the quality of tumour image and correlation with known sites of disease has been compared by scanning with the two agents in a variety of malignant diseases. In addition, comparative

The pharmacodynamics of technetium-99m stannous citrate were studies in Yale-Swiss mice bearing a sarcoma-like transplantable brain tumor, and the renal kinetics were determined in normal mice. Using a rating system based on tumor uptake and tumor-to-brain, tumor-to-blood, and tumor-to-skin ratios,

Biological distribution of 103Ru in mice bearing Ehlrich's solid tumor and rats bearing AH-130 solid tumor were studied with two compounds of 103Ru, the chloride and citrate. The radioactivity of 103Ru-chloride showed slower excretion and higher tumor concentration than that of citrate. The

Intraspinal narcotic (usually intrathecal morphine) infusions with implanted pumps are increasingly used in patients with intractable chronic pain not caused by cancer. In some patients, pain control is difficult with infusions of morphine. Seven patients with diagnoses of arachnoiditis, epidural

Radioiodinated bleomycin is a chemically stable radiopharmaceutical that can be prepared with high specific activity using 123I. Its pharmacokinetics were compared with those of 99mTc,- 111In-, and 57Co-bleomycin, and 67Ga citrate in mice bearing a transplanted KHJJ tumor. The in vivo kinetics and

The pharmacokinetics of 67Ga-citrate, 111In-bleomycin, *I-bleomycin, and *I-fibrinogen were compared in a murine KHJJ tumor model in order to assess their relative potential as agents for in vivo detection of cancer. Although all four agents have been reported to be clinically efficacious, in this

Breast cancer in males is comparatively rare. A 41-year-old man visited our hospital with a complaint of left breast tumor. Initial examination showed remarkably diffuse metastatic lesions in the lung field and small metastatic lesions in the surrounding skin. Modified radical mastectomy, including

We report a case ofa 60-year old male esophageal cancer patient who was unable to take oral medication, but was successfully treated using a fentanyl citrate buccal tablet. The patient survived a suicide attempt as a youth in which he ingested poison, but was left with a stricture of the esophagus.

The uptake of the tumor scanning agent 67-Ga citrate by cultured mouse tumor cells wqs greatly enhanced with small additons of certain sera to the culture medium. This stimulation of uptake was due to a macromolecular serum component, provisionally identified with transferrin. The response under