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SEQUENCE LISTING
The nucleic and amino acid sequences listed in the accompanying Sequence Listing are presented in accordance with 37 C.F.R. 1.822. The Sequence Listing is submitted as an ASCII computer readable text file, created on May 1, 2013 as 4 KB, which is incorporated by reference
SEQUENCE LISTING
The nucleic and amino acid sequences listed in the accompanying Sequence Listing are presented in accordance with 37 C.F.R. 1.822. Only one strand of each nucleic acid sequence is shown, but the complementary strand is understood as included by any reference to the displayed strand.
BACKGROUND OF THE INVENTION
Cysteine proteases, such as cathepsins B, L, S, and O.sub.2, have been implicated in a number of diseases, including cancer metastasis and invasion (Clin. Exp. Metastasis 1992, 10, 145-155; Cancer Metastasis Rev. 1990, 9, 333-352), arthritis (Int. J. Biochem. 1993, 25,
FIELD OF THE INVENTION
This invention relates to novel protease inhibitor conjugates and antibodies useful in immunoassay. More specifically, this invention relates to novel activated haptens useful for generating immunogens to HIV protease inhibitors, to novel immunogens useful for producing
The present invention relates to a three component-mixed vaccine which comprises as the antigens OEP (Original Endotoxin Protein) obtained from Pseudomonas aeruginosa, an elastase toxoid obtained from P. aeruginosa and a protease toxoid obtained from P. aeruginosa. The three component-mixed vaccine
TECHNICAL FIELD OF THE INVENTION
This invention relates to an anticoagulant isolated from hookworms.
BACKGROUND OF THE INVENTION
Hookworms are intestinal nematodes that infect over 1 billion persons worldwide, with a higher prevalence in children than in adults (briefly reviewed in Cecil's Textbook
FIELD OF THE INVENTION
The present invention relates to the identification of a gene (CLN2) which, when mutated, results in the neurodegenerative disease classical late infantile neuronal ceroid lipofuscinosis (LINCL). CLN2 encodes a pepstatin-insensitive carboxyl protease which is a 46 kDa lysomal
FIELD OF THE INVENTION
The present invention relates to the identification of a gene (CLN2) which, when mutated, results in the neurodegenerative disease classical late infantile neuronal ceroid lipofuscinosis (LINCL). CLN2 encodes a pepstatin-insensitive carboxyl protease which is a 46 kDa lysomal
FIELD OF THE INVENTION
The present invention relates to the identification of a gene (CLN2) which, when mutated, results in the neurodegenerative disease classical late infantile neuronal ceroid lipofuscinosis (LINCL). CLN2 encodes a pepstatin-insensitive carboxyl protease which is a 46 kDa lysomal
FIELD OF THE INVENTION
The present invention relates to the identification of a gene (CLN2) which, when mutated, results in the neurodegenerative disease classical late infantile neuronal ceroid lipofuscinosis (LINCL). CLN2 encodes a pepstatin-insensitive carboxyl protease which is a 46 kDa lysomal
FIELD OF THE INVENTION
The present invention relates to the identification of a gene (CLN2) which, when mutated, results in the neurodegenerative disease classical late infantile neuronal ceroid lipofuscinosis (LINCL). CLN2 encodes a pepstatin-insensitive carboxyl protease which is a 46 kDa lysomal
FIELD OF THE INVENTION
This invention relates to novel compounds and their pharmaceutically acceptable acid addition salts and base addition salts for use in the treatment of acne, common cold, inflammatory joint disease by inhibition of cysteine proteases and cysteine activity dependent enzymes. In
FIELD OF THE INVENTION
This invention relates to novel compounds and their pharmaceutically acceptable acid addition salts and base addition salts for use in the treatment of acne, common cold, inflammatory joint disease by inhibition of cysteine proteases and cysteine activity dependent enzymes. In
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to novel foodstuffs derived from soymilk, a method for the production thereof, and uses found therefor.
More particularly, this invention relates to novel foodstuffs produced by a method which comprises causing a specific
This application is a National Stage of PCT/JP10/073342 filed Dec. 24, 2010 and claims the benefit of JP 2009-295466 filed Dec. 25, 2009.
TECHNICAL FIELD
The present invention relates to soy sauce having hypotensive effects that contains no hypotensive agent. More particularly, the present invention