5 结果
A 36-year-old patient with chronic active hepatitis developed Coombs direct positive acute hemolytic anemia 2 weeks after a second course of cyanidanol (Cy). The patient's serum agglutinated control 0 Rh- erythrocytes only in the presence of Cy. Human anti-globulin test showed that the red cells
Five patients who received cyanidanol for 4-36 months are presented. Three developed both hemolytic anemia and thrombocytopenia, while 2 had only thrombocytopenia. After suspending the drug the hematological values returned to normal in all of the patients. Drug-dependent platelet antibodies were
The serological findings of three patients suffering from liver cirrhosis and hepatitis accompanied by immunohemolytic anemia (IHA) are described. As a cause of the observed hemolyses the administration of (+)-Cyanidanol-3 (Catergen) was supposed. In contrast to three cases reported in literature
Several episodes of acute intravascular immune hemolysis in a 68 year old patient induced by (+)-cyanidanol-3 (Catergan) are reported. Clinical and serological criteria of the so-called immune-complex mechanism of immune drug-induced hemolysis were realised. The meaning of the additional marked