cyanidanol 3/atrophy

The clinically effective hepatoprotective flavonoid, (+)-Cyanidanol-3, prevented the Fe2+-induced functional deterioration of rat liver mitochondria. Fe2+ treatment of mitochondria resulted in increased lipid peroxidation (MDA-formation), decreased mitochondrial membrane potential, impaired Ca2+

The (+)-cyanidanol-3 is used as an antihepatotoxic and hepatoprotective drug in both men and animals against alcoholic and experimental liver injury. Histologic staining techniques give mostly qualitative or semiquantitative description of liver damages. Experiments have been carried out to

The antinecrotic potential of a new drug, 3-palmitoyl-(+)-catechin (PC), which is a derivative of (+)-cyanidanol-3, was studied in two different experimental models of necrosis of the liver in the rat: acute hepatitis induced by galactosamine and liver damage induced by a combination of chronic