cysteine/seizures

One third of patients with idiopathic autism have treatment resistant epilepsy, associated with earlier onset of seizures. In addition to insufficient response to medical treatment, they also have poorer responses to surgical and VNS approaches (Sansa et al 2011). Novel approaches to reduce seizure

Niemann-Pick Disease, type C (NPC) is an autosomal recessive lysosomal storage disease with progressive neurodegeneration. It is characterized by intracellular accumulation of cholesterol and glycosphingolipids. The age of onset is variable with cases manifesting from infancy to adulthood.

Patients who attend the antenatal care clinic at Assiut University Hospital were recruited and counseled about participating in the study. A written informed consent was taken. Patients had the right to refuse to participate and/or withdraw from the study at ay time without being denied their