d sorbitol/dental caries

Most toothpastes contain either d-sorbitol or glycerin, or both, as humectants. Both compounds are about half as sweet as sucrose. This level of sweetness is not as intense as desired by most people when brushing teeth. Therefore, many brands of toothpaste add saccharin, a high-intensity sweetener,

Dental caries is one of the most common infectious diseases that affects humans. Streptococcus mutans, the main pathogenic bacterium associated with dental caries, produces a number of extracellular sucrose-metabolizing enzymes, such as glucosyltransferases (GTFB, GTFC and GTFD) and

Lycasin was included in diets fed to caries-active Osborne-Mendel rats for periods up to 8 weeks. The animals could tolerate up to 15-16% of Lycasin in dry-powder diets and up to 25% in pelleted diets before gastro-intestinal disturbance. Lycasin 80/55 at 25% in the diet was non-cariogenic,

The solubility of various Ca(II) salts, hydroxyapatite, and powdered human dental enamel in the presence of simple carbohydrates was studied by determining the complex strength between Ca(II) and the carbohydrates. In 1.0 M CaSO4, the following simplified sequence of complex strengths was obtained

Six bacterial strains isolated from the human oral cavity, PPPA16, PPPA20(T), PPPA24, PPPA31, EPPA6 and EPPA7, were characterized by determining phenotypic and biochemical features, cellular fatty acid profiles, menaquinone profiles and phylogenetic position based on 16S rRNA gene sequence analysis.

OBJECTIVE To evaluate the utility of insoluble powder formulation for nasal systemic drug delivery. METHODS To compare the efficacy of liquid and powder formulations, the nasal absorption of drugs was examined in rats using hydrophilic compounds with various molecular weights (MW) such as phenol

Human metabolism of D-fructose, D-sorbitol, D-mannitol, and xylitol has been documented. In humans, sorbitol and xylitol at a single oral dose of 20 g or less and fructose at 70 g or less most likely can be fully absorbed. These there sugars can maintain, either independently or nearly