exsanguination/arginine

OBJECTIVE To investigate the effects of the long-term oral administration of L-arginine on the impaired neurogenic and endothelium-dependent relaxation responses of corpus cavernosum smooth muscle from alloxan-induced diabetic rabbits. METHODS Thirty-two New Zealand white rabbits were used in four

BACKGROUND This study was designed to evaluate the combined effects of hyperbaric oxygen (HBO) and N-acetylcysteine (NAC) on acute necrotizing pancreatitis in rats. METHODS Experiments were performed in 50 male Wistar rats, which were divided into five groups (N = 10 for each group). The first group

The endogenous nitric oxide (NO) synthase (NOS) inhibitor asymmetrical dimethylarginine (ADMA) is elevated in many patients and may contribute to the initiation and progression of their disease. While some mechanistic pathways have been identified, tissue-specific contributions to ADMA control

The evolution of trauma care is driven by a synergistic relationship between civilian and military medical systems. Although the characteristics of civilian injuries differ from those encountered on the battlefield, the pathophysiologic process of dying is the same and dominated by exsanguination

During cardiopulmonary bypass (CPB), showers of microemboli (ME) distribute among the organs and connective tissues according to regional blood flow. Post CPB, ME were quantified by subtracting residual platelets (RP) in the organs of a group of unoperated control Yorkshire pigs (n = 6) from those

To investigate the metabolic and organ changes accompanying growth of a malignant tumor, ten male Fisher 344 rats weighing 150 to 200 g were inoculated subcutaneously with 10(6) viable MCA sarcoma cells (tumor-bearing). Ten other rats (controls) were similarly inoculated with saline. Both groups

OBJECTIVE To investigate the regulatory mechanisms responsible for autoregulation of retinal blood flow (RBF) during periods of decreased ocular perfusion pressure (OPP). METHODS The effects of acute reductions in OPP on RBF were assessed using laser Doppler velocimetry in cats. The OPP decreased