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Changes of microcirculatory perfusion in rats following cold injury of right hind leg under hypoxia were investigated. Male Wistar rats weighing 200 +/- 20 g were randomly divided into three groups: frostbite at normoxia (FN) group; frostbite during acute hypoxia (4 h at 6000 m simulated altitude,
It was found that cold injury in rats acclimated to hypoxia was more serious than that in nonacclimated ones. In order to go further into the cause, blood rheological parameters in rats of frostbite at normoxia (FN), frostbite during acute hypoxia (FAH) and frostbite during hypoxia after hypoxic
The changes of some factors of blood coagulation system in rats following frost-bite of both hind feet under hypoxia were investigated. Male Wistar rats weighed 200 +/- 20g were divided into four groups: normal control (C); frostbite at normoxia (FN); frostbite during acute hypoxia (FAH) and
Frostbite is frequently seen in high altitude climbers. Many Sherpas, members of an ethnic community living high in the Himalayas in Nepal, help the climbers as a guide or an assistant. They often seem to undertake few precautionary measures thus suffer more from frostbite. A young Sherpa, who had
BACKGROUND
A literature review was conducted to analyze developments in the epidemiology, pathogenesis, treatment, and prevention of frostbite injury. Increased participation in outdoor activities, as well as the epidemic of homelessness, makes knowledge of the treatment of frostbite crucial for
Jones, Daniel, Samuel F. Covins, Gavin E. Miller, Kenneth I. Morrison, Alexander G. Clark, Samuel D. Calcott, Alasdair M. Anderson, Samuel J.E. Lucas, Christopher H.E. Imray, and the Warwick Altitude Research Group. Infrared red thermographic analysis of surface temperature of the hands during
Effect of exposure to acute hypoxia and hypoxia for 2 weeks on the skin temperature and content of glycogen of frostbitten feet in rabbits were observed. The results showed that the skin temperatures and content of glycogen were decreased in frostbite at normoxia (FN) group frostbite during acute
A new rectal cooling device for therapeutic hypothermia (TH) therapy is designed and is applied in TH treatment of SD rats with ischemic-hypoxic brain damage.
Healthy adult SD rats (n = 45) were randomly assigned into four groups: the healthy control group (n = 5), the ischemia and hypoxia group (n
OBJECTIVE
Pathophysiologic changes of frostbite have been postulated but rarely understood, especially the changes caused by chilly high altitude environment. Therefore, we investigated the pathophysiologic changes of high altitude frostbite (HAF) caused by cold and hypoxia.
METHODS
Forty
Serum creatine kinase (CK) activity after cold exposure in rats acclimated to cold, hypoxia, or combined factors (both cold and hypoxia) were observed under normoxic [correction of normoxie] and hypoxic condition in order to study the degrees of damage to the tissues. The results showed that
During a 10-year period (December 1984 to December 1994), 1500 cases of frostbite were treated at a tertiary care medical facility. They were all males with their ages ranging from 17 to 43 years. All the patients sustained the frostbite injury in the northeastern part of Pakistan known as the
BACKGROUND
Hypoxia and hypothermia are acknowledged risk factors for those who venture into high-altitude regions. There is, however, little in situ data that can be used to quantify these risks. Here, we use 7 months of continuous meteorological data collected at the South Col of Mount Everest
In brief The body's response to severe brief cold-protecting the core temperature by reducing circulation to the extremities-makes the feet vulnerable to frostbite. A frostbitten foot should be rewarmed only when there is no danger of refreezing. During rewarming, patients may need heavy sedation as
BACKGROUND
People suffer unique health problems in high altitude areas, due to such factors as elevation, aircraft ascent and descent, extreme cold, hypoxia, hypobaria, and low relative humidity. This study was conducted to evaluate ENT morbidity at high altitude.
METHODS
Serving soldiers introduced