giant/inflammation

Giant cells are commonly seen in granulomas produced by a wide variety of known and unknown agents. It is widely accepted that giant cell formation results from fusion of mononuclear phagocytes. Both experimental and circumstantial evidence suggests that fusion takes place following the attachment

Inflammatory fibroid polyps are uncommon but well documented polypoid lesions occurring in gastrointestinal tract, most commonly in the stomach followed by ileum and rarely in the colon, duodenum or esophagus, especially in the sixth decade of life. The lesions are characterized by variable

A 42-year-old woman presented with a clinically obvious giant rhinophyma. The protocol of the unit handling the case mandated that all lesions amenable to biopsy should have a core biopsy before any definitive surgery, but the unnecessary biopsy was not representative and suggested an incorrect

Aphthae are single or multiple small painful ulcers, preceded by a burning sensation, with a yellow background surrounded by a non-indurated red border, healing usually in 8-10 days. They usually affect the buccal mucosa, but sometimes they are bipolar (orogenital) with possible variants: deep

Bronchial inflammatory polyps are defined as tumor-like lesions. They are usually related to chronic inflammatory processes in the adult. Because they may cause complications, they should be surgically removed. A 55-year-old male patient had been followed for recurrent pulmonary infections for 40

OBJECTIVE Despite shorter replacement intervals and new lens materials, giant papillary conjunctivitis still limits the ability of some patients to wear contact lenses. RESULTS Recent research has elucidated many new mediators of inflammation. The presence of chemokines and cytokines such as IL-8,

A case of giant gallbladder is presented. A 36-yr-old female complaining of colicky pain and a mass in the right upper quadrant underwent cholecystectomy, when the giant gallbladder, 18 cm in length and 4 cm in maximum diameter, and an extremely long cystic duct was confirmed. Since neither marked

Giant cell arteritis is a generalized inflammatory disorder involving large and medium-sized arteries. The etiology is unknown, although an autoimmune pathogenesis seems probable. In view of the clinical similarities between patients with positive biopsy findings for polymyalgia rheumatica and those

Giant cell myocarditis (GCM) as a distinct disease entity has been questioned. The superficial morphologic resemblance to cardiac sarcoidosis and incomplete histopathologic assessment of extracardiac organ systems in reported cases has suggested that GCM represents a predominant cardiac

This review summarizes the diagnosis, clinical manifestations and management of giant cell arteritis. Giant cell arteritis is an immune-mediated vasculitis of medium to large sized arteries that affects individuals older than the age of 50. Patients typically present with signs of vascular