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TECHNICAL FIELD
This invention relates to inhibitors of protein tyrosine phosphatase 1B (PTP1B) and other protein tyrosine phosphatases (PTPases).
BACKGROUND
Protein tyrosine phosphatases (PTPases) are a large family of diverse molecules that can play an important role in modulating a wide variety
This invention concerns compositions of RNA functioning as an RNA enzyme, i.e. a ribozyme in several capacities: dephosphorylase (acid phosphatase and transphosphorylase), ribonucleotidyl transferase (polymerase activity) and sequence-specific endoribonuclease activities.
SUMMARY
It is found that
This invention concerns compositions of RNA functioning as an RNA enzyme, i.e. a ribozyme in several capacities: dephosphorylase (acid phosphatase and transphosphorylase), ribonucleotidyl transferase (polymerase activity) and sequence-specific endoribonuclease activities.
SUMMARY
It is found that
This invention concerns compositions of RNA functioning as an RNA enzyme, i.e. a ribozyme in several capacities: dephosphorylase (acid phosphatase and transphosphorylase), ribonucleotidyl transferase (polymerase activity) and sequence-specific endoribonuclease activities.
SUMMARY
It is found that
This invention concerns compositions of RNA functioning as an RNA enzyme, i.e. a ribozyme in several capacities: dephosphorylase (acid phosphatase and transphosphorylase), ribonucleotidyl transferase (polymerase activity) and sequence-specific endoribonuclease activities.
SUMMARY
It is found that
The cystic fibrosis (also referred to hereafter by the abbreviation "CF"), also named mucoviscidosis, is a most serious autosomal recessive genetic disease, particularly frequent in the populations of European origin. About one child in 2,000-2,500 children is in France affected by this disease. The
I. FIELD OF THE INVENTION
Embodiments of this invention include the use of a specific class of chemically synthesized compounds and alkaline phosphatase, separately or in combination with each other and other therapies, to selectively decrease the viability of non-healthy cells, particularly cancer
TECHNICAL FIELD
This invention relates generally to a novel cell line, and specifically to a novel rat osteosarcoma cell line, as well as its use for screening for cell growth factors or cell differentiation factors.
BACKGROUND OF THE INVENTION
Polypeptide growth factors play a key role in
I. FIELD OF THE INVENTION
Embodiments of this invention include the use of a specific class of chemically synthesized compounds and alkaline phosphatase, separately or in combination with each other and other therapies, to selectively decrease the viability of non-healthy cells, particularly cancer
TECHNICAL FIELD
This invention relates generally to a novel cell line, and specifically to a novel rat osteosarcoma cell line, as well as to certain growth factors produced by the cell line.
BACKGROUND OF THE INVENTION
Polypeptide growth factors play a key role in regulating the development of
TECHNICAL FIELD
This invention relates generally to a novel cell line, and specifically to a novel rat osteosarcoma cell line, as well as to certain growth factors produced by the cell line.
BACKGROUND OF THE INVENTION
Polypeptide growth factors play a key role in regulating the development of
TECHNICAL FIELD
This invention relates generally to a novel cell line, and specifically to a novel rat osteosarcoma cell line, as well as to certain growth factors produced by the cell line.
BACKGROUND OF THE INVENTION
Polypeptide growth factors play a key role in regulating the development of
TECHNICAL FIELD
This invention relates generally to a novel cell line, and specifically to a novel rat osteosarcoma cell line, as well as to certain growth factors produced by the cell line.
BACKGROUND OF THE INVENTION
Polypeptide growth factors play a key role in regulating the development of
TECHNICAL FIELD
This invention relates generally to a novel cell line, and specifically to a novel rat osteosarcoma cell line, as well as to certain growth factors produced by the cell line.
BACKGROUND OF THE INVENTION
Polypeptide growth factors play a key role in regulating the development of
FIELD OF THE INVENTION
This invention relates to the concept of functionally hyperactive red/far-red light sensor genes such as a modified phytochrome A (PHYA) nucleic acid molecule of which a serine/threonine amino acid at the hinge region between the amino- and the carboxy-domains and at the