3 结果
In search of effective antidiabetic agents having therapeutic effect by inhibiting α-glucosidase and preventive effect by scavenging free radicals, Horsfieldia macrobotrys showed promising bioactivity required for the proposed criteria. Bioassay-guided isolation of the stem bark extract resulted in
Horsfieldia macrobotrys Merr has long been used by Dayak people in East Kalimantan of Indonesia, for diabetes therapy. Inspired by ethnopharmacological use and promising α-glucosidase and radical scavenging activities, an attempt to identify the active components was carried out. Bioassay-guided
In search for effective antidiabetic agents that simultaneously inhibit α-glucosidase and scavenge free radicals, Horsfieldia motleyi showed promising bioactivity according to the proposed criteria. Bioassay-guided isolation of pericarp extract yielded a new 4-arylflavan named myristinin G (6),