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indian tobacco/nicotine

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Carcinogenic tobacco-specific nitrosamines in Indian tobacco products.

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Various Indian tobacco products--cigarette, bidi, chutta and their smoke, chewing tobacco and snuff (used for inhalation as well as a dentifrice) were analysed for their content of tobacco-specific nitrosamines (N'-nitrosonornicotine, 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone and
Occupational sickness among tobacco farmers due to the handling of green tobacco leaves is termed "green symptom." This symptom was investigated among 197 Indian tobacco workers and it was found that 88.83% of the workers were suffering from green symptom when exposed to green tobacco leaves during
BACKGROUND Oral cancer is one of the five leading sites of cancer in the Indian population. In the present study we analyzed the expression of apoptosis regulating genes, viz. survivin, Bcl-2, Bax and p53 in precancerous and cancerous lesions of the buccal mucosa of Indian tobacco
Oral cancer is the leading cancer type among Southeast Asian men and is causally associated with the use of tobacco. Genetic polymorphisms in xenobiotic-metabolizing enzymes modify the effect of environmental exposures, thereby playing a significant role in gene-environment interactions and hence
BACKGROUND Oral cancer is the sixth most common malignancy in the world. Viruses are the causative agents of approximately 10-15% of all cancers worldwide (Cancers, 6, 2014 and 2155). The tumorigenic roles of Epstein-Barr virus in oral cancer are unclear. Literature search results are conflicting
OBJECTIVE Nuclear microsatellite markers were developed for Lobelia inflata (Campanulaceae), an obligately self-fertilizing plant species, for use in the study of temporal fluctuation in allele frequency and of the genetic structure within and among populations. • RESULTS We developed 28 primer
The timing of reproduction is an important life-history variable, especially for organisms that die following a single reproductive episode, such as the monocarp Lobelia inflata. The propensity to initiate flowering (to bolt) under a given set of conditions is expected to be shaped by natural

Arsenic adulteration in Indian tobacco.

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Sixty samples of smoking and chewing tobacco from subjects in and around Ludhiana, Punjab were tested for arsenic content. No significant difference between the two groups could be detected. The probable role of arsenicosis in neuropathy and liver disease in the Indian population is discussed.

Mutagenic potential of Indian tobacco products.

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The mutagenic potential of aqueous extracts of masheri (ME), chewing tobacco alone (CTE) and a mixture of chewing tobacco plus lime (CTLE) was tested using the Ames assay. ME exhibited mutagenicity in Salmonella typhimurium TA98 upon metabolic activation with aroclor-1254-induced rat liver S9, while

Intervention studies against "green symptoms" among Indian tobacco harvesters.

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The use of rubber gloves reduced nicotine and cotinine absorption among 29 tobacco harvesters, as evidenced by the urinary excretion rate of nicotine and cotinine. Approximately 20% (n = 6) of the subjects reported that symptoms disappeared when they used gloves, but the remaining 23 workers
Tobacco is chewed in the form of snuff and thus its radioactivity--if there is any--goes directly into the body. Besides normal smoking, tobacco is also smoked in reverse manner in the form of "chutta", an indigenously prepared cigar made from the home grown plants of Nicotinia tobacum in South East
Inter-individual genetic differences may contribute to differences in susceptibility to human diseases triggered by environmental exposures. In this study, we investigated polymorphisms at two sites in the CYP1A1 and three sites in the CYP2E1 genes in 99 leukoplakia patients and 227 controls from
Radon contents in some samples of tobacco, tea and tooth powder have been estimated using CR-39 solid state nuclear track detectors. The Radon content in tobacco has been found to vary from 14.06 +/- 1.4 to 89.91 +/- 3.3 mBq/l. The Radon content in tea and tooth powder has been found to vary from
The diets of 158 tobacco/betel quid-chewing women diagnosed with oral premalignant lesions and 155 quid-chewing but lesion-free controls, frequency matched for age, tobacco/betel habits, and socioeconomic status, were assessed using a food frequency survey. Index scores generated from the food
BACKGROUND Tobacco users face barriers not just in quitting, but also in thinking about quitting. The aim of this study was to understand factors encouraging intention to quit from the 2006 International Tobacco Control Policy (TCP) Evaluation India Pilot Study Survey. METHODS A total of 764 adult
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