The delayed intervention group was to benefit from the intervention after week 8.

Chikungunya Virus Infection

The wait-list group benefit from a 8-week yoga program after the interventional group

Wait-list group

During 8 weeks, the intervention group attended weekly yoga sessions and had to practice poses at home

Yoga group

Mouffias' Medical Center in Guadeloupe.

Yoga for Chronic Chikungunya

Impact of Yoga on Quality of Life in Patients With Chronic Chikungunya: A Randomized Controlled Study

This scale measures eight health domains (Physical Functioning, Role-Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role-Emotional, Mental Health) of quality of life for adults aged 18 and older. Using a scoring algorithm, the aggregated scores can provide two summary scores: the physical component summary (PCS) score and the mental component summary (MCS) score.

The Visual Analog Scale (VAS) is a 10 cm line with anchor statements on the left (no pain) and on the right (extreme pain). The patient is asked to mark their current pain level on the line. They can also be asked to mark their maximum, minimum, and average pain. The examiner scores the VAS by measuring the distance in either centimeters (0 to 10) or millimeters (0 to 100) from the "no pain" anchor point.

The total score is calculated as the sum of the 10 items and the cut-off value for the diagnosis of neuropathic pain is a total score of 4/10.

Centre Hospitalier Universitaire de Pointe-a-Pitre

Children 6-59 months with bilateral pitting edema, and/or WHZ < - 3 and/or MUAC < 115 mm.

Severe Malnutrition

Comparison of outcomes between children with complicated SAM and children with uncomplicated SAM as well as comparisn of outcomes against national and internationally agreed upon standards of care

Therapeutic feeding for children with SAM

Atal Bal State Nutrition Mission and National Rural Health Mission

Integrated Program for Children With Severe Acute Malnutrition in Madhya Pradesh, India

Evaluation of the Effectiveness of an Integrated Program for the Management of Severe Acute Malnutrition in Children in Madhya Pradesh, India

Weight gain >= 15% of initial weight gain

Proportion of children completing a 14-day stay in the NRC, transitioned to the community phase of the program and atteding at least two of the four community-based follow up visits.

Average weight gain per Kg body mass per day during stay in the programme

Victor M. Aguayo

Chief, Child Nutrition and Development, India

Gandhi Medical College, Bhopal

Bundelkhand Medical College, Sagar, Madhya Pradesh

Gajara Raja Medical College

Drug: 12- Weeks of Prednisolone Therapy Subjects will add an additional 12 weeks of Prednisolone to follow pre-randomization standard of care prednisolone. Post randomization Prednisolone therapy of 30 mg/m2 on alternate days for 4 weeks, 20 mg/m2 on alternate days for 4 weeks, and 10 mg/m2 on alternate days for 4 weeks

Subjects will NOT receive 12-weeks of additional Prednisolone therapy following randomization

Nephrotic Syndrome

Prednisolone for 12 weeks as follows 30 mg/m2 on alternate days for 4 weeks 20 mg/m2 on alternate days for 4 weeks 10 mg/m2 on alternate days for 4 weeks

Prednisolone

Cedars-Sinai Medical Center, Pediatric IBD & Pediatric Nephrology

Stanford University Medical Center, Department of Pediatrics, Division of Nephrology

University of Michigan Department of Pedatric Nephrology

Levine's Children/Carolinas HealthCare System

All India Institute of Medical Sciences

Prednisolone Trial in Children Younger Than 4 Years

Randomized, Multicentric, Open Label, Parallel Group Trial to Compare the Efficacy of 6-months Versus 3-months Therapy With Prednisolone for the First Episode of Idiopathic Nephrotic Syndrome in Children Younger Than 4 Years

Proportion of patients with one or more relapse(s) of nephrotic syndrome

Number of nephrotic syndrome relapses per patient year during the 12-month period following randomization

Number of days from randomization to occurrence of first relapse

Proportion of patients with frequent relapses during the 12 months post randomization

Total amount of prednisolone [or corticosteroid equivalent] received, as mg/kg/day or mg/m2/day as intervention and for treatment of relapses, during 12 months from randomization

The proportion of patients in each study arm treated with steroid-sparing strategies or medications, e.g., levamisole, cyclophosphamide, mycophenolate mofetil and calcineurin inhibitors

Number and types of adverse events experienced, related or unrelated to corticosteroid use

Changes in standard deviation scores (SDS) for weight, height and body mass index during 12-month period following randomization

Proportions of B (naive, memory, regulatory) and T (cytotoxic, helper 1, helper 2, helper 17, regulatory) cell subsets, as determined by flow cytometric staining for specific surface and intracellular markers

Number of nephrotic syndrome relapses per patient year during the 24-month period

Proportion of patients with frequent relapses during the 24 months post randomization

Total amount of prednisolone [or corticosteroid equivalent] received, as mg/kg/day or mg/m2/day as intervention and for treatment of relapses, during 24 months from randomization

Proportion of patients with one or more relapse(s) of nephrotic syndrome in boys compared to girls

Proportion of patients with one or more relapse(s) of nephrotic syndrome in patients <2-yr-old at randomization compared to older patients

Proportion of patients with one or more relapse(s) of nephrotic syndrome in Indian patients compared to those in the USA

Number of nephrotic syndrome relapses per patient year during the 12-month period in boys compared to girls

Number of nephrotic syndrome relapses per patient year during the 12-month period in patients <2-yr-old at randomization compared to older patients

Number of nephrotic syndrome relapses per patient year during the 12-month period in Indian patients compared to those in the USA

Number of days from randomization to occurrence of first relapse in boys compared to girls

Number of days from randomization to occurrence of first relapse in patients <2-yr-old at randomization compared to older patients

Number of days from randomization to occurrence of first relapse in Indian patients compared to those in the USA

Proportion of patients with frequent relapses during the 12 months post randomization in boys compared to girls

Proportion of patients with frequent relapses during the 12 months post randomization in patients <2-yr-old at randomization compared to older patients

Proportion of patients with frequent relapses during the 12 months post randomization in Indian patients compared to those in the USA

Total amount of prednisolone [or corticosteroid equivalent] received, as mg/kg/day or mg/m2/day as intervention and for treatment of relapses, during 12 months from randomization in boys compared to girls

Total amount of prednisolone [or corticosteroid equivalent] received, as mg/kg/day or mg/m2/day as intervention and for treatment of relapses, during 12 months from randomization in patients <2-yr-old at randomization compared to older patients

Total amount of prednisolone [or corticosteroid equivalent] received, as mg/kg/day or mg/m2/day as intervention and for treatment of relapses, during 12 months from randomization in Indian patients compared to those in the USA

Following anonymisation to protect patient identity, data from patients in USA will be pooled and analyzed with that from Indian patients. Data will be available once all subjects have completed the study and data has been analyzed. No interim data analysis will be conducted

Arvind Bagga

Professor, Department of Pediatrics

All India Institute of Medical Sciences, New Delhi

NephCure Accelerating Cures Institute

University of Michigan

Multicentric, Parallel group, Open label randomized controlled trial

Hemodialysis Complication

Hemodialysis

Saint-Georges Hospital

Twice Against Thrice-weekly Hemodialysis

Twice-Against Thrice-weekly Hemodialysis: the TATH Trial

Rate of supplementary hemodialysis sessions for pulmonary oedema or hyperkalemia

Rate of uncontrolled hypertension, Uncontrolled hypertension is defined as a pre-dialysis BP > 160/90 in more than 2/3 of the sessions.

indian/edema

Yoga for Chronic Chikungunya

Integrated Program for Children With Severe Acute Malnutrition in Madhya Pradesh, India

Prednisolone Trial in Children Younger Than 4 Years

Twice Against Thrice-weekly Hemodialysis

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