indian/neoplasms

INTRODUCTION This invention relates generally to the field of antineoplastic compounds and more particularly to the synthesis of pentapeptide amides exhibiting antineoplastic effects. BACKGROUND OF THIS INVENTION Ancient marine invertebrate species of the Phyla Bryozoa, Molluska, and Porifera have

BACKGROUND OF THE INVENTION 1. Field of the Invention This invention concerns a complex prescription of Chinese medicine for the treatment of extensive cancer 2. Description of the Related Art The medicine for the treatment of cancers with certain effect has still not been found in the market or

INTRODUCTION The present invention relates generally to cell growth inhibition and more particularly to a potent cell growth inhibitory substance herein denominated "Dolastatin 10" which is obtained from the Indian Ocean sea hare Dolabella, to pharmaceutical preparations containing Dolastatin 10 as

INTRODUCTION The present invention relates to cytostatic linear and cyclo-depsipeptides herein denominated "Dolastatin 16," "Dolastatin 17," and "Dolastatin 18" which are obtained from the Indian Ocean shell-less mollusk Dolabella auricularia; and to methods of using such substances to inhibit

BACKGROUND OF THE INVENTION A great number of ancient marine invertebrate species in the Phyla Bryozoa, Mollusca and Porifera were well established in the earth's oceans over one billion years ago. Certainly such organisms had explored trillions of biosynthetic reactions in their evolutionary

INTRODUCTION The present invention relates to the discovery and isolation of compounds extracted from the marine sponge Spirastrella spinispirulifera (Class Demospongiae, Order Hadromerida, Family Spirastrellidae). These new macrocyclic lactones are designated herein as "spongistatin 5",

INTRODUCTION This invention relates generally to a newly discovered compound which is found to inhibit the growth of various selected human cell lines tumors by the National Cancer Institute. More specifically, this invention relates to a new polyether macrolide of the halipyran-type which was

CROSS-REFERENCE TO RELATED APPLICATIONS This application is a National Stage of International patent application PCT/EP2010/062809, filed on Sep. 1, 2010, which claims priority to foreign French patent application No. FR 09 04476, filed on Sep. 18, 2009, the disclosures of each of which are

BACKGROUND OF THE INVENTION A great number of ancient marine invertebrate species in the Phyla Bryozoa, Mollusca and Porifera were well established in the earth's oceans over one billion years ago. Certainly such organisms have explored trillions of biosynthetic reactions in their evolutionary

BACKGROUND OF THE INVENTION The rapidly intensifying search for biologically and medicinally important marine organism constituents has attracted a great deal of interest world-wide. Not unexpectedly, a reassuring number of marine animals, plants and microorganisms are being found to produce