3 结果
OBJECTIVE
To study the chemical constituents of the root of Salvia przewalakii.
METHODS
The chemical constituents were isolated and purified by means of chromatographic techniques and their structures were elucidated by spectroscopic methods.
RESULTS
17 compounds were isolated and identified as
Cholinesterase inhibition is one of the most treatment strategies against Alzheimer's disease (AD) where metal accumulation is also strongly associated with pathology of the disease. In the current study, we assessed inhibitory effect against acetyl- (AChE) and butyrylcholinesterase (BChE) and
The known diterpenes 12,16-epoxycarnosol (2), isotanshinone II (6), and (+)-neocryptotanshinone (8) were obtained by partial synthesis from 16-hydroxycarnosol (1), a C-16 hydroxylated abietatriene diterpene isolated in relative abundance from the aerial part of Salvia mellifera GREENE. The physical