jaundice/hypoxia

OBJECTIVE The aim of the present study was to investigate the expression of intercellular adhesion molecule-1 (ICAM-1) by sinusoidal endothelial cells (SECs) during hypoxia-reoxygenation in an obstructive jaundice model. METHODS Male Wistar rats aged 6 to 8 weeks were assigned to an obstructive

The release of cytokine by Kupffer cells during hypoxia/reoxygenation was studied in vitro in male Wistar rats with obstructive jaundice to investigate the kinetics of interleukin-8 (IL-8) release by Kupffer cells during hypoxia/reoxygenation, and to study the influence of endotoxin during the

Maximum serum bilirubin concentration and the possible influencing factors were studied in three groups of preterm infants suffering from hyaline membrane disease. The groups were selected according to the severity of hypoxia, estimated on clinical grounds. It was found that the severity of hypoxia

The article is devoted to the problem of efficacy of the hepatic insufficiency (HI) prophylaxis and treatment methods in obturation jaundice. The role of energy-depending processes and the oxygen deficiency in tissues in the HI occurrence and progressing, the possibilities of medicinal correction of

Efficacy of application of oxygen-transporting preparations in the treatment of obturation jaundice was studied. In experimental conditions while modelling obturation jaundice in animals there were revealed signs of failure of the oxygen delivery to hepatic cells, shown by significant lowering of

High serum bilirubin levels (SBL), over 20-25 mg/dl are toxic for the Central Nervous System (CNS) of newborn infants. However, the possible toxicity on the CNS of "intermediate" SBL both in term and preterm neonates are still a matter of debate. An extensive review of the literature in this respect

BACKGROUND Chronic hypoxemia is generally attributed to primary cardiac or pulmonary entities. METHODS A 9-year-old boy presenting with cyanosis, clubbing and hypoxemia, without icterus or hepatosplenomegaly. Cardiovascular and respiratory system examinations were normal. RESULTS He was diagnosed as

The increase in the maternal plasma A.F.P. level is due to an hypoxia of the foetus. The prospective study of 851 single pregnancies shows that there is a significant rise in the A.F.P. levels during the last days of the pregnancy if the babies are going to exhibit a so-called physiological jaundice

Five patients are described in whom deep jaundice developed following severe trauma. Only two of the patients showed acute renal failure. All showed the adult respiratory distress syndrome. The livers at autopsy were enlarged and showed centrilobular congestion and cholestases. This syndrome, which

In cases of neonatal obstructive jaundice, liver biopsy material has been studied electronmicroscopically. In bile duct atresia, morphologic changes are extensive and they develop early. The severity of destruction is related to the quantity of accumulated bile deposits. Hypoxia due to the

Erythrocyte damage of newborn babies suffering from hyperbilirubinaemia and hypoxia was compared with a control group. In the cases of serum bilirubin level higher than physiological icterus lipid peroxidation of erythrocytes decreased probably due to the antioxidant effect of bilirubin. Moreover,