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jaundice/obesity

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10 结果

The University of Zimbabwe College of Health Science (UZ-CHS) BIRTH COHORT Study

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Over one million infants are born to HIV-1-infected women every year in Sub Saharan Africa. In Zimbabwe, annual births stand at 379,000 with approximately 48,000 infants being born every year to HIV-1-infected women on lifelong highly active antiretroviral therapy (HAART). Concerns have been

Microvesicles and Monocytes to Predict Mortality of Patients With Cirrhosis

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Natural history of cirrhosis Cirrhosis is the end stage form of chronic liver disease. It is estimated that 200,000 to 500,000 people in France have cirrhosis. Cirrhosis is responsible for more than 170,000 deaths per year in Europe. The main causes of cirrhosis include excessive alcohol

Stratification of Risk of Diabetes in Early Pregnancy

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High glucose level in Pregnancy or Gestational Diabetes Mellitus (GDM) is one of the most common medical conditions during pregnancy. When undetected, it can cause significant harm for the pregnant women and her offspring. GDM can affect 5-25% of all pregnant women. It depends on the population and
Severe alcoholic hepatitis is associated with significant morbidity and mortality. Diagnosis: The diagnosis of (AH) is made by the following criteria11 I.Chronic active alcohol abuse - > 80 grams in males and > 20 grams in females. II. Duration of jaundice < 3 months III. Serum Bilirubin >5 mg/dl

Inhibition of VAP-1 by Caffeine in Healthy Human Volunteers Study

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One such enzyme known as VAP-1 (vascular adhesion protein-1) is expressed at high levels in liver endothelial cells and studies involving blockage of VAP-1 activity have demonstrated it is involved in a reaction where break down products such as hydrogen peroxide and ammonia active signalling

Liver Transplantation in Alcoholic Hepatitis

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This is a open prospective multicenter study. Nineteen liver transplant units in Spain will take part in it. Inclusion criteria for patients: 1. Diagnosis of alcoholic hepatitis (liver biopsy will be advisable). 2. First episode of clinical decompensation of alcoholic liver disease (defined as

Study of Offspring of Women With Type 1 Diabetes

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Introduction Health conditions result from a combination of genetic susceptibility and environmental influences. While the genotype is determined at conception the phenotype is modulated and influenced by environmental and epigenetic factors throughout life, not only postnatally but already in uteri

Effect of Adipokines in Hemodialysis Patients

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Randomization: 100 overweight or obese patients will be randomly allocated to oral pioglitazone 15 mg/d or placebo for two weeks by blocks of five using a random number generator and monitored for adverse events including hypoglycemia. If they tolerate the 15 mg pioglitazone or matching placebo for
PLAN: Women who present for prenatal care are routinely screened for gestational diabetes (GDM) with a one-hour 50gm oral glucose challenge test (GCT). This screening occurs at the first prenatal visit if risk factors (marked obesity, prior pregnancy affected by GDM, prior macrosomic infant,

Insulin and Biogenic Amines in Cardiovascular Disease

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BACKGROUND: The Normative Aging Study (NAS) is a multidisciplinary longitudinal study of aging established by the Veterans Adminstration in 1963. Six thousand male volunteers from the Greater Boston area were screened for acceptance into the study according to laboratory, clinical, radiologic and
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