lobetyol/codonopsis

BACKGROUND In this study, we investigated whether lobetyolin, lobetyol, and methyl linoleate derived from Codonopsis pilosula affect MUC5AC mucin secretion, production, and gene expression from airway epithelial cells. METHODS Confluent NCI-H292 cells were pretreated with lobetyolin, lobetyol, or

Although Codonopsis pilosula (C. pilosula) has long been considered as an important herbal medicine, no analytical method of marker compounds for quality assessment is registered in the Korean Pharmacopoeia. We developed a simple and robust analytical method of three marker components lobetyolin

A new neolignan, (-)-(7R,8S,7'E)-3',4-dihydroxy-3-methoxy-8,4'-oxyneoligna-7'-ene-7,9,9'-triol(1), and seven known compounds, 9-(tetrahydropyran-2-yl)-nona-trans,trans-2,8-diene-4,6-diyn-1-ol (2), 9-(tetrahydropyran-2-yl)-trans-non-8-ene-4,6-diyn-1-ol (3), lobetyol (4), lobetyolin

Chemical examination of the n-butanol extract of the root of Codonopsis tangshen led to the isolation of four new compounds named codonosides A (1) and B (2) and codonopyrrolidiums A (3) and B (4), with seven known compounds [(Z)-2-(beta-glucopyranosyloxy)-3-phenylpropenoic acid (5), lobetyolin (6),

BACKGROUND Codonopsis Radix is commonly used as a tonic in traditional Chinese medicine. However, there is no suitable method to assess the quality of Codonopsis Radix based on multiple components having potential bioactivities. OBJECTIVE To establish a HPLC/UV method for simultaneous quantitation

A comparative study of 56 specimens of three medicinally-used Codonopsis taxa collected from China and 54 commercial samples of Codonopsis Radix available in Chinese, Japanese and Korean markets was carried out by quantitative analysis of seven major components: codonopyrrolidium B (1),