lycoctonine/delphinium

THE TITLE COMPOUND [SYSTEMATIC NAME: 6β,10-dihy-droxy-1α,14α,16β-trimeth-oxy-4-methyl-7β,8-(methyl-enedi-oxy)-20-ethyl-aconitan-6-yl acetate], C(27)H(41)NO(8), is a C(19)-diterpenoid alkaloid and a major diterpenoid alkaloid component of the roots of Delphinium delavayi Franch. var. pogonanthum

Aerial parts of a collection of Delphinium pentagynum Lam. from Niebla, Southern Spain, furnished one diterpene alkaloid, 2-dehydrodeacetylheterophylloidine, two norditerpene alkaloids, 14-demethyl-14-isobutyrylanhweidelphinine and 14-demethyl-14-acetylanhweidelphinine, the known alkaloids

Three new norditerpenoid alkaloids, nordhagenine A (1), nordhagenine B (2), and nordhagenine C (3), along with a known alkaloid, lycoctonine, were isolated from the aerial parts of Delphinium nordhagenii. The structures of the new compounds 1 and 2 were also deduced on the basis of single-crystal

A new minor diterpenoid alkaloid, caeruline, was isolated from DELPHINIUM CAERULEUM Jacq. ex Camb. Its structure was elucidated as 1 on the basis of spectral evidence. Along with this new compound, three known diterpenoid alkaloids were also isolated from this plant and identified as tatsiensine,

The present study was designed to determine the chemical constituents of Delphinium caeruleum Jacq. ex Camb.. The chemical constituents were isolated and purified by column chromatography with silica gel, ODS, and Sephadex LH-20. Their structures were elucidated by IR, MS, and NMR. Ten compounds

From the roots of Delphinium potaninii var. jiufengshanense, two new lycoctonine-type C(19)-diterpenoid alkaloids called jiufengdine (1) and jiufengtine (4) have been isolated. The structures of the new alkaloids (1, 4) were established by 1D and 2D NMR spectra.

Further studies on the chemical constituents of Delphinium potaninii roots led to the isolation of two new lycoctonine-type norditerpenoid alkaloids, potanisines A (1) and B (3). The structures of these compounds were determined by interpretation of the spectroscopic data. They are the first

A new lycoctonine diterpenoid alkaloid navicularine, along with eighteen known diterpenoid alkaloids, were isolated from the whole plant of Delphinium naviculare var. lasiocarpum. Their structures were elucidated on the base of extensive spectroscopic analysis (HR-ESI-MS and NMR) and comparison with

Chemical investigation of the CHCl(3) extracts from the roots of Delphinium scabriflorum has resulted in the isolation of a new diterpenoid alkaloid, 13-(2-methylbutyryl)azitine (1), along with 11 known alkaloids, delbine (2), 14-deacetyl-14-isobutyrylajadine (3), methyllycaconitine (4),

OBJECTIVE To study the chemical constituents isolated from the roots of Delphinium grandiflorum L. var. leiocarpum W. T. Wang. METHODS The constituents were isolated and purified by various chromatographic methods and their structures were identified by spectral analysis. RESULTS Five known

A new franchetine-type (leueandine 1) and two new lycoctonine-type [potanisines F (3) and G (5)] C19-diterpenoid alkaloids have been isolated from the roots of Aconitum hemsleyanum var. leueanthus and Delphinium potaninii, respectively, and their structures were established on the basis of spectral

Between 1995 and 1999, several cattle of a group of 80 heifers died acutely on a pasture in the Swiss Alps. The animals were Found dead between July 9th and 15th eachyear. Only 1 animal was examined on post-mortem, and no significant lesions were found. Aconitum vulpera, A napellus, and Delphinium

The title compound, C(26)H(39)NO(7), which was isolated from Delphinium anthriscifolium var. majus, has a lycoctonine carbon skeleton containing four six-membered rings (A, B, D and E) and three five-membered rings (C, F and G). Rings A, B and E adopt chair conformation, while ring D adopts a boat

Two new norditerpenoid alkaloids with lycoctonine skeleton, anthriscifolcones A (1) and B (2), were isolated from the whole plant of Delphinium anthriscifolium var. Majus by extensive column chromatography. Their structures were established by IR, MS, (1)H NMR, (13)C NMR, and 2D NMR methods

Early studies have shown that some of diterpenoid alkaloids, found in highly toxic plants of the genera Aconitum and Delphinium, act at neuronal nicotinic acetylcholine receptors (nAChRs) and exhibit potent N-cholinolytic activity. In the current study, GA-MLRA and GA-PLS approaches have been used