mallotus philippensis/potassium

The slow delayed rectifier potassium current (I Ks ) is formed by the KCNQ1 (K v 7.1) channel, an ion channel bearing four α-subunits and modulating KCNE1 β-subunits. I Ks is central in the repolarization of the cardiac action potential. Loss of function mutation reducing ventricular cardiac I Ks

BACKGROUND Mallotus oppositifolius is a shrub that is used traditionally to treat epilepsy, but its potential has not been scientifically validated. OBJECTIVE This study investigated the anticonvulsant properties and possible mechanism of action of the 70% v/v hydroalcoholic extract of the leaves of