methemoglobinemia/nicotine

Aromatic amines, toxic agents causing methemoglobinemia and human carcinogens (2-naphtylamine, 2-toluidine), are present in mainstream (MS) and sidestream (SS) tobacco smoke. Because of this fact, active and passive smokers are exposed to them. The aim of this study was to assess exposure of active

BACKGROUND Iron is involved in important vital functions as an essential component of the oxygen-transporting heme mechanism. In this study we aimed to evaluate whether oxidative metabolites from maternal cigarette smoke could affect iron homeostasis in the brain of victims of sudden unexplained

Ensuring patient safety under time pressure Key words: on-time starts, turnover time, briefing, team communication, delays. Holes in the outer layer of sterilization wraps Key words: package integrity, defects, sterilization wrap, contaminated item, sterile field. Changing surgical attire after

BACKGROUND Surgery is supposed to modulate the production of carbon monoxide by the reduction of heme oxygenase activity or transcriptional regulation of inducible heme oxygenase. On the other hand, the inhalation of tobacco smoke can substantially raise the level of carboxyhemoglobin in the blood.

Arylamines (AAs) and heterocyclic aromatic amines (HAAs) are structurally related carcinogens formed during the combustion of tobacco or cooking of meat. They undergo cytochrome P450 mediated N-hydroxylation to form metabolites which bind to DNA and lead to mutations. The N-hydroxylated metabolites

The main objective of this paper is to discuss the environmental issues in the countries of central and eastern Europe (CCEE) and to show their significance for cancer epidemiology. Of known cancer risk factors that may be related to environmental exposure in the CCEE, tobacco smoking is probably