4 结果
Quantitation of cholesterol and its precursors from human adipose tissue biopsies revealed very high squalene and moderately high methyl sterol concentrations. The squalene and cholesterol values were correlated with each other. Weight reduction in obese subjects following a jejuno-ileal bypass
Serum squalene and methyl sterols (cholesterol precursors), and the fractional conversion of mevalonate to cholesterol (FCM) were determined after an i.v. injection of a labelled mevalonate-labelled cholesterol mixture in fifteen studies in eleven subjects with varying cholesterol synthesis rates
Cardiovascular disease (CVD) is the Nation's leading killer for both men and women among all racial and ethnic groups. Development and progression of CVD is linked to the presence of risk factors such as hyperlipidemia, hypertension, obesity, and diabetes mellitus. It is known that cholesterol is an
A markedly-high cholesterol production characterizes human obesity. So far, the site of origin of this extra synthesis has not been defined, even though the liver may play an important role. A marked expansion of adipose tissue in obesity raises a question on the local cholesterol synthesis,