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mirabilis hirsuta/化学疗法

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文章临床试验专利权
4 结果
Swarmer cells of the Gram-negative uropathogenic bacteria Proteus mirabilis and Vibrio parahaemolyticus become long (>10 to 100 μm) and multinucleate during their growth and motility on polymer surfaces. We demonstrated that the increasing cell length is accompanied by a large

[Sensitivity of Proteus mirabilis to drugs in the presence of human blood serum].

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For rational antibiotic therapy of patients with persisting bacterial infections, the routine determination of antibiotic resistance in the microorganisms may be insufficient. In this case estimation of the total bactericidal activity of the antibacterial drugs and sera against the causative agents
A simple method was used for testing the antibiotic susceptibility of adherent bacteria to plastic surfaces. Pseudomonas aeruginosa, Serratia marcescens, and Proteus mirabilis cells adhering to the bottom of a plastic tissue culture plate were incubated in serially diluted antibiotic solutions.

Experimental pyelonephritis induced by L-forms of Proteus mirabilis in rats.

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Pyelonephritis was produced in 75 white rats by applying a 24-hour ligature on the ureter and by intravenous injection of a suspension of 5X10(9) cells of a stable Proteus mirabilis L-form. Pyelonephritis was proved microscopically in 44% of the animals. The revertants of the introduced L-form play
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