3 结果
Ricin induced apoptotic nuclear morphological changes in mouse macrophage cell line RAW264.7 cells at concentrations sufficient to cause severe protein synthesis inhibition. Ricin also induced the release of tumor necrosis factor-alpha (TNF-alpha) from this cell line in a dose-dependent manner but
Suicide transport is a term applied to the technique of producing anatomically selective neural lesions using axonally transported cytotoxins. Because the cytotoxic lectins, abrin, modeccin and volkensin are effective suicide transport agents in the peripheral nervous system, the present study
The effects of cytotoxic lectins, modeccin and phytohemagglutinin (PHA) on mouse macrophage cell line RAW264.7 was studied by detecting the induction of inflammatory mediators. Results showed that modeccin induced the release of tumor necrosis factor-α (TNF-α) from RAW264.7 cells with a bell-shape