3 结果
Mondia whitei is an African traditional spice with aphrodisiac properties. Inhibition of mitochondrial permeability transition (mPT) pore is an important cytoprotective process essential for cell survival. In this study, the effects of methanol extract (ME), dichloromethane (DCMF), ethyl acetate
OBJECTIVE
To determine the effect of the aqueous extract of Mondia whitei (Periplocaceae) roots on testosterone production and fertility of male rats.
METHODS
Adult male Wistar rats were used. In the acute study, 20 rats were randomly divided into 5 groups of 4 animals each. Four treated groups were
Chronic administration of Mondia whitei L. root bark extract (400 mg/kg/day) for 55 days caused testicular lesions resulting in the cessation of spermatogenesis, degenerative changes in the seminiferous tubules and epididymides. The wet weight of the seminal vesicle increased, whereas the weights of