3 结果
This is a single-center, pilot feasibility study of NR supplementation in allogeneic (donor) HCT in which the study team is seeking to obtain preliminary data on any beneficial effect of increasing NAD+ levels in-vivo to facilitate engraftment. Engraftment is defined as the process during which
At the current time there is no effective disease modifying therapy for diabetic neuropathy (DN). Previous failed trials of therapy have often targeted individuals with advanced, severe neuropathy. There is a particularly strong incentive to treat neuropathy early in its course while the severity is
Study design and overview - This is a laboratory-based study. The investigators plan to establish a list of host cellular proteins regulating norovirus infection. Methods will include establishment of patient-specific stem cell-derived human intestinal enteroids as an infection model and genome-wide