niemann-pick diseases/griffonia simplicifolia

We have compared the pattern of lectin staining with the ultrastructural features of kidneys from normal cats and 19 cats with 6 different lysosomal storage diseases. The diseases studied include GM1 and GM2 gangliosidosis, mucopolysaccharidosis (MPS)-I and MPS-VI, sphingomyelin-lipidosis (i.e.,

Kidney and liver samples from two cases of Fabry's disease and spleen and liver samples from Gaucher and Niemann-Pick diseases were tested for binding to lectins such as peanut agglutinin (PNA), Bandeiraea simplicifolia, (BSA), canavalia ensiformis (Con A), soybean agglutinin (SBA) and wheat germ