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BACKGROUND
Serum alkaline phosphatase (ALP) has been shown to be a prognostic factor in several subgroups of patients due to its promotion of vascular calcification. However, the prognostic impact of serum ALP level in ST-segment elevation myocardial infarction (STEMI) patients with a relatively low
Background: Elevated serum transaminase or alkaline phosphatase (ALP) has been proposed as a novel prognosticator for ST-segment elevation myocardial infarction (STEMI). We evaluated the combined prognostic impact of elevated serum transaminases and ALP on
The inflammatory cytokines interleukin (IL)-10 and tumor necrosis factor (TNF)-α play an important role in left ventricular (LV) remodeling after myocardial infarction (MI). Phosphatase and tensin homolog deleted on chromosome ten (PTEN) inactivates protein kinase Akt and promotes cell death in the
BACKGROUND
There has been increasing evidence suggesting that lipopolysaccharide or endotoxin may be an important activator of the innate immune system after acute myocardial infarction. Bovine intestinal alkaline phosphatase reduces inflammation in several endotoxin mediated diseases by
BACKGROUND
Alkaline phosphatase (ALP) removes phosphate groups from many types of molecules. The aim of the present research was to study the relation between plasma ALP and survival in diabetic patients with myocardial infarction.
METHODS
Retrospective study: from 954 admissions (15 months period)
The spectrum of acid phosphatase isoenzymes was studied by means of disk electrophoresis in polyacrylamide gel. Seven isofractions were detected of this enzyme in blood plasma. In patients with the acute stage of myocardial infarction the amount of isofraction 3 was increased, its electrophoretic
Ten consecutive cases of acute transmural myocardial infarction were accompanied by a rise of 50 to 400 percent in the serum acid phenylphosphatase. The increase in phosphatase began several hours after onset of symptoms and lasted 3 to 5 days. A similar rise was seen during the acute stages of
Serum creatine phosphokinase (CK) and alkaline phosphatase (ALP) rise after mesenteric infarction; it is not known which one rises earlier or which one has the greater elevation. This experiment compared and contrasted the elevations in both these enzyme systems after acute small bowel infarction.
: PP1-12, a new protein phosphatase-1 inhibitor, is designed and synthesized to modulate the endoplasmic reticulum (ER) stress apoptotic pathway, which is involved in various cardiovascular diseases. In this study, we examined the effect of PP1-12 on ventricular remodeling and heart function after
BACKGROUND
The role of protein phosphatases (PPs) during ischemic preconditioning in the rabbit heart was examined.
RESULTS
Fostriecin, a potent inhibitor of PP2A, was administered to isolated rabbit hearts starting either 15 minutes before or 10 minutes after the onset of a 30-minute period of
Extremely high concentration, 172-hold the upper limit of reference range, of serum prostate-specific acid phosphatase was measured by radioimmunoassay in a patient subsequently shown to have prostatic infarction associated with prostatic hyperplasia. Following retropubic prostatectomy, the serum
The relation of total serum alkaline phosphatase and serum cholesterol in convalescing patients of myocardial infarction with secretor status and blood groups have been studied. Serum cholesterol and alkaline phosphatase levels showed significant difference in secretors (98) and nonsecretors (56) in
Leucocytic acid phosphatase (AP) activity was measured cytochemically in 21 myocardial-infarction patients aged 37 to 57. Neutrophil leucocytosis was found to result from an increase in the quantity of cells with high activity of the enzyme. Neutrophil AP activity was elevated during the first days
OBJECTIVE
To determine how prostatic infarcts affect serum prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP) levels.
METHODS
Two hundred eighteen clinically benign, whole prostates were obtained at autopsy, completely sectioned, and examined histologically. PSA and PAP levels were
Objective Recent studies have shown that alkaline phosphatase (ALP) might play a negative role in clinical outcomes of patients with peripheral and coronary artery disease. This study aimed to investigate the relationship between serum ALP levels and coronary thrombolysis in myocardial infarction