4 结果
A preliminary pharmacological screening of the methanolic extract of Picralima nitida fruit was carried out. The extract showed potent and dose-dependent anti-inflammatory, antipyretic and anti-malarial activities. Given intraperitoneally, it inhibited carrageenan-induced rat paw oedema with IC50 of
Pseudo-akuammigine, an alkaloid from Picralima nitida seed extract was investigated for anti-inflammatory and analgesic actions using the carrageenan-induced rat paw oedema and the rat tail flick. The alkaloid, at 1.0, 5.0 and 50 mgkg(-1)(,) dose-dependently inhibited the mean maximal paw swelling
Picralima nitida Durand and Hook, (fam. Apocynaceae) is a West African plant with varied applications in African folk medicine. Various parts of the plant have been employed ethnomedicinally as remedy for fever, hypertension, jaundice, dysmenorrheal, gastrointestinal disorders and malaria. In order
Objectives Blend of seeds and leaves of Picralima nitida herein referred to as West African Durand powder (WDP) was investigated for antinociceptive and anti-inflammatory properties. Methods Acute toxic effect of the aqueous extract was evaluated in mice of both sexes. Antinociceptive effect of WDP