Among BHC isomers (benzene hexachloride, C6H6Cl6, theoretically eight ones), seven isomers (α,β,γ,δ,ε,η,ι) including one racemate (α) were isolated and their configurations were elucidated. Among the seven isomers, only γ-BHC has a potent insecticidal activity. γ-BHC poisoning symptoms accompanied
Ligand-gated chloride channels underlie inhibition in excitable membranes and are proven target sites for insecticides. The gamma-aminobutyric acid (GABA(1)) receptor/chloride ionophore complex is the primary site of action for a number of currently used insecticides, such as lindane, endosulfan,