poa/抗抑郁药

Citalopram is the most potent selective serotonin reuptake inhibitor (SSRI) which is used as an antidepressant but causes sexual dysfunction. Whether citalopram induced sexual dysfunction is a result of gonadotropin-releasing hormone (GnRH), kisspeptin or RF-amide related peptide (RFRP) alteration

BACKGROUND Evidence is accumulating globally on harms from extramedical prescription opioid analgesic (POA) use. OBJECTIVE The aim of this scoping review was to explore harms and documented risk factors associated with extramedical POA use in Australia. METHODS MEDLINE, EMBASE, PsycINFO and CINAHL

The decrease in serotonergic neurotransmission during aging can increase the risk of neuropsychiatric diseases such as depression in elderly population and decline the reproductive system. Therefore, it is important to understand the age-associated molecular mechanisms of brain aging. In this study,

In order to elucidate the mechanism of anti-muricide action of psychotropic drugs in the brain, the present study examined influences of these drugs microinjected into the hypothalamus on muricide. Inhibition of muricide by chlorpromazine (CPZ) was found both in the lateral preoptic area (1-POA) and

Tianeptine is an atypical tricyclic antidepressant that facilitates serotonin (5-HT) reuptake. Tianeptine (10 mg/kg) or saline was administered intraperitoneally to male rats daily for 4 days. Monoamine levels were measured in micropunches of discrete brain nuclei that are implicated in mood and